rs79605584

Homo sapiens
G>A
HDAC5 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0044 (1340/29924,GnomAD)
A=0049 (1451/29118,TOPMED)
A=0047 (237/5008,1000G)
A=0037 (142/3854,ALSPAC)
A=0032 (120/3708,TWINSUK)
chr17:44122308 (GRCh38.p7) (17q21.31)
CD
GWASdb2
1   publication(s)
See rs on genome
465 Enhancers around
19 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 17NC_000017.11:g.44122308G>A
GRCh37.p13 chr 17NC_000017.10:g.42199676G>A

Gene: HDAC5, histone deacetylase 5(minus strand)

Molecule type Change Amino acid[Codon] SO Term
HDAC5 transcript variant 3NM_001015053.1:c.N/AIntron Variant
HDAC5 transcript variant 1NM_005474.4:c.N/AIntron Variant
HDAC5 transcript variant X8XM_005256905.1:c.N/AIntron Variant
HDAC5 transcript variant X7XM_005256906.4:c.N/AIntron Variant
HDAC5 transcript variant X10XM_011524149.1:c.N/AIntron Variant
HDAC5 transcript variant X10XM_011524150.1:c.N/AIntron Variant
HDAC5 transcript variant X1XM_017023988.1:c.N/AIntron Variant
HDAC5 transcript variant X2XM_017023989.1:c.N/AIntron Variant
HDAC5 transcript variant X3XM_017023990.1:c.N/AIntron Variant
HDAC5 transcript variant X4XM_017023991.1:c.N/AIntron Variant
HDAC5 transcript variant X5XM_017023992.1:c.N/AIntron Variant
HDAC5 transcript variant X6XM_017023993.1:c.N/AIntron Variant
HDAC5 transcript variant X11XM_017023995.1:c.N/AIntron Variant
HDAC5 transcript variant X11XM_017023996.1:c.N/AIntron Variant
HDAC5 transcript variant X9XM_017023994.1:c.N/AGenic Upstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.908A=0.092
1000GenomesAmericanSub694G=0.970A=0.030
1000GenomesEast AsianSub1008G=0.955A=0.045
1000GenomesEuropeSub1006G=0.974A=0.026
1000GenomesGlobalStudy-wide5008G=0.953A=0.047
1000GenomesSouth AsianSub978G=0.970A=0.030
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.963A=0.037
The Genome Aggregation DatabaseAfricanSub8702G=0.924A=0.076
The Genome Aggregation DatabaseAmericanSub838G=0.960A=0.040
The Genome Aggregation DatabaseEast AsianSub1622G=0.958A=0.042
The Genome Aggregation DatabaseEuropeSub18460G=0.969A=0.030
The Genome Aggregation DatabaseGlobalStudy-wide29924G=0.955A=0.044
The Genome Aggregation DatabaseOtherSub302G=0.940A=0.060
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.950A=0.049
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.968A=0.032
PMID Title Author Journal
23958962Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.Gelernter JMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs796055840.000149cocaine dependence23958962

eQTL of rs79605584 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs79605584 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr174214976442149814E067-49862
chr174215030042150497E067-49179
chr174215055342150613E067-49063
chr174215067442150760E067-48916
chr174216400442165249E067-34427
chr174217393142174023E067-25653
chr174217445742175844E067-23832
chr174217723342177333E067-22343
chr174217738642177605E067-22071
chr174217768242177781E067-21895
chr174217883542179194E067-20482
chr174217927642179345E067-20331
chr174218032442180872E067-18804
chr174218090142181021E067-18655
chr174218176042181950E067-17726
chr174218203442182258E067-17418
chr174218227842182377E067-17299
chr174218254042182605E067-17071
chr174218284642183809E067-15867
chr174218393042183984E067-15692
chr174218429442184375E067-15301
chr174218466542184737E067-14939
chr174218500842187352E067-12324
chr174219095842191117E067-8559
chr174219126842191343E067-8333
chr174219142142191522E067-8154
chr174219168342192136E067-7540
chr174219218742192270E067-7406
chr174219242542192485E067-7191
chr174219251942192569E067-7107
chr174219259242192709E067-6967
chr174219275942192940E067-6736
chr174219298342193419E067-6257
chr174219342142193533E067-6143
chr174219355342193689E067-5987
chr174219374342193803E067-5873
chr174219381042193860E067-5816
chr174219410042194150E067-5526
chr174219416342194213E067-5463
chr174219421442194354E067-5322
chr174219457842195141E067-4535
chr174219527042195320E067-4356
chr174219534142195499E067-4177
chr174219578542195888E067-3788
chr174219600842196559E067-3117
chr174219656142196833E067-2843
chr174219697142197159E067-2517
chr174219717342197302E067-2374
chr174219755442197633E067-2043
chr174219766442197752E067-1924
chr174219778742197876E067-1800
chr174219804342198083E067-1593
chr174220195042202003E0672274
chr174221515842216398E06715482
chr174224545442246279E06745778
chr174216386142163940E068-35736
chr174216400442165249E068-34427
chr174217393142174023E068-25653
chr174217445742175844E068-23832
chr174217652442176638E068-23038
chr174217664942176737E068-22939
chr174217679242176842E068-22834
chr174217711242177193E068-22483
chr174217723342177333E068-22343
chr174217738642177605E068-22071
chr174217883542179194E068-20482
chr174217927642179345E068-20331
chr174217938042179476E068-20200
chr174218032442180872E068-18804
chr174218090142181021E068-18655
chr174218176042181950E068-17726
chr174218203442182258E068-17418
chr174218227842182377E068-17299
chr174218254042182605E068-17071
chr174218284642183809E068-15867
chr174218466542184737E068-14939
chr174218500842187352E068-12324
chr174218768542190742E068-8934
chr174219095842191117E068-8559
chr174219126842191343E068-8333
chr174219142142191522E068-8154
chr174219168342192136E068-7540
chr174219218742192270E068-7406
chr174219242542192485E068-7191
chr174219251942192569E068-7107
chr174219259242192709E068-6967
chr174219275942192940E068-6736
chr174219298342193419E068-6257
chr174219342142193533E068-6143
chr174219355342193689E068-5987
chr174219578542195888E068-3788
chr174219600842196559E068-3117
chr174219656142196833E068-2843
chr174219697142197159E068-2517
chr174219717342197302E068-2374
chr174219755442197633E068-2043
chr174219766442197752E068-1924
chr174219778742197876E068-1800
chr174219804342198083E068-1593
chr174220195042202003E0682274
chr174221515842216398E06815482
chr174224545442246279E06845778
chr174216340342163753E069-35923
chr174216386142163940E069-35736
chr174216400442165249E069-34427
chr174217224442172326E069-27350
chr174217234142172391E069-27285
chr174217393142174023E069-25653
chr174217445742175844E069-23832
chr174217723342177333E069-22343
chr174217738642177605E069-22071
chr174217768242177781E069-21895
chr174217927642179345E069-20331
chr174217938042179476E069-20200
chr174217961342179673E069-20003
chr174218000542180084E069-19592
chr174218032442180872E069-18804
chr174218090142181021E069-18655
chr174218176042181950E069-17726
chr174218203442182258E069-17418
chr174218227842182377E069-17299
chr174218254042182605E069-17071
chr174218284642183809E069-15867
chr174218500842187352E069-12324
chr174218768542190742E069-8934
chr174219095842191117E069-8559
chr174219126842191343E069-8333
chr174219142142191522E069-8154
chr174219168342192136E069-7540
chr174219218742192270E069-7406
chr174219242542192485E069-7191
chr174219251942192569E069-7107
chr174219259242192709E069-6967
chr174219275942192940E069-6736
chr174219298342193419E069-6257
chr174219342142193533E069-6143
chr174219355342193689E069-5987
chr174219374342193803E069-5873
chr174219381042193860E069-5816
chr174219410042194150E069-5526
chr174219416342194213E069-5463
chr174219421442194354E069-5322
chr174219457842195141E069-4535
chr174219527042195320E069-4356
chr174219534142195499E069-4177
chr174219578542195888E069-3788
chr174219600842196559E069-3117
chr174219656142196833E069-2843
chr174219697142197159E069-2517
chr174219717342197302E069-2374
chr174221515842216398E06915482
chr174224485342245034E06945177
chr174224505042245140E06945374
chr174224519242245369E06945516
chr174224545442246279E06945778
chr174214976442149814E070-49862
chr174215030042150497E070-49179
chr174215055342150613E070-49063
chr174215067442150760E070-48916
chr174217445742175844E070-23832
chr174217738642177605E070-22071
chr174217768242177781E070-21895
chr174218203442182258E070-17418
chr174218227842182377E070-17299
chr174218254042182605E070-17071
chr174218284642183809E070-15867
chr174218500842187352E070-12324
chr174218768542190742E070-8934
chr174219095842191117E070-8559
chr174219126842191343E070-8333
chr174219142142191522E070-8154
chr174219168342192136E070-7540
chr174219218742192270E070-7406
chr174219534142195499E070-4177
chr174219578542195888E070-3788
chr174219600842196559E070-3117
chr174219656142196833E070-2843
chr174219697142197159E070-2517
chr174219717342197302E070-2374
chr174224545442246279E07045778
chr174214976442149814E071-49862
chr174215030042150497E071-49179
chr174215055342150613E071-49063
chr174215067442150760E071-48916
chr174215424842154358E071-45318
chr174215438042154438E071-45238
chr174215461942154692E071-44984
chr174215500042155192E071-44484
chr174215557042155639E071-44037
chr174215767042157710E071-41966
chr174215791542158003E071-41673
chr174215813242158258E071-41418
chr174216400442165249E071-34427
chr174217070142171018E071-28658
chr174217125742171334E071-28342
chr174217156642171616E071-28060
chr174217203842172088E071-27588
chr174217224442172326E071-27350
chr174217234142172391E071-27285
chr174217393142174023E071-25653
chr174217445742175844E071-23832
chr174217711242177193E071-22483
chr174217723342177333E071-22343
chr174217738642177605E071-22071
chr174217883542179194E071-20482
chr174217927642179345E071-20331
chr174218032442180872E071-18804
chr174218090142181021E071-18655
chr174218176042181950E071-17726
chr174218203442182258E071-17418
chr174218227842182377E071-17299
chr174218254042182605E071-17071
chr174218284642183809E071-15867
chr174218393042183984E071-15692
chr174218429442184375E071-15301
chr174218466542184737E071-14939
chr174218500842187352E071-12324
chr174218768542190742E071-8934
chr174219095842191117E071-8559
chr174219126842191343E071-8333
chr174219142142191522E071-8154
chr174219168342192136E071-7540
chr174219218742192270E071-7406
chr174219242542192485E071-7191
chr174219251942192569E071-7107
chr174219259242192709E071-6967
chr174219275942192940E071-6736
chr174219298342193419E071-6257
chr174219342142193533E071-6143
chr174219355342193689E071-5987
chr174219374342193803E071-5873
chr174219381042193860E071-5816
chr174219410042194150E071-5526
chr174219416342194213E071-5463
chr174219421442194354E071-5322
chr174219457842195141E071-4535
chr174219527042195320E071-4356
chr174219534142195499E071-4177
chr174219578542195888E071-3788
chr174219600842196559E071-3117
chr174219656142196833E071-2843
chr174219697142197159E071-2517
chr174219717342197302E071-2374
chr174219755442197633E071-2043
chr174219766442197752E071-1924
chr174219778742197876E071-1800
chr174219804342198083E071-1593
chr174221515842216398E07115482
chr174224485342245034E07145177
chr174224505042245140E07145374
chr174224519242245369E07145516
chr174224545442246279E07145778
chr174224732342248646E07147647
chr174217224442172326E072-27350
chr174217234142172391E072-27285
chr174217393142174023E072-25653
chr174217445742175844E072-23832
chr174217723342177333E072-22343
chr174217738642177605E072-22071
chr174218090142181021E072-18655
chr174218176042181950E072-17726
chr174218203442182258E072-17418
chr174218227842182377E072-17299
chr174218254042182605E072-17071
chr174218284642183809E072-15867
chr174218429442184375E072-15301
chr174218466542184737E072-14939
chr174218768542190742E072-8934
chr174219095842191117E072-8559
chr174219126842191343E072-8333
chr174219142142191522E072-8154
chr174219168342192136E072-7540
chr174219218742192270E072-7406
chr174219242542192485E072-7191
chr174219251942192569E072-7107
chr174219259242192709E072-6967
chr174219275942192940E072-6736
chr174219298342193419E072-6257
chr174219342142193533E072-6143
chr174219355342193689E072-5987
chr174219374342193803E072-5873
chr174219381042193860E072-5816
chr174219410042194150E072-5526
chr174219416342194213E072-5463
chr174219421442194354E072-5322
chr174219457842195141E072-4535
chr174219527042195320E072-4356
chr174219534142195499E072-4177
chr174219578542195888E072-3788
chr174219600842196559E072-3117
chr174219656142196833E072-2843
chr174219697142197159E072-2517
chr174219804342198083E072-1593
chr174219814242199476E072-200
chr174224485342245034E07245177
chr174224505042245140E07245374
chr174224519242245369E07245516
chr174224545442246279E07245778
chr174224732342248646E07247647
chr174216386142163940E073-35736
chr174216400442165249E073-34427
chr174217393142174023E073-25653
chr174217445742175844E073-23832
chr174217617042176220E073-23456
chr174217652442176638E073-23038
chr174217664942176737E073-22939
chr174217679242176842E073-22834
chr174217883542179194E073-20482
chr174217927642179345E073-20331
chr174217938042179476E073-20200
chr174218032442180872E073-18804
chr174218090142181021E073-18655
chr174218176042181950E073-17726
chr174218203442182258E073-17418
chr174218227842182377E073-17299
chr174218254042182605E073-17071
chr174218284642183809E073-15867
chr174218393042183984E073-15692
chr174218768542190742E073-8934
chr174219095842191117E073-8559
chr174219126842191343E073-8333
chr174219142142191522E073-8154
chr174219168342192136E073-7540
chr174219218742192270E073-7406
chr174219242542192485E073-7191
chr174219251942192569E073-7107
chr174219259242192709E073-6967
chr174219275942192940E073-6736
chr174219298342193419E073-6257
chr174219342142193533E073-6143
chr174219355342193689E073-5987
chr174219374342193803E073-5873
chr174219381042193860E073-5816
chr174219410042194150E073-5526
chr174219416342194213E073-5463
chr174219421442194354E073-5322
chr174219457842195141E073-4535
chr174219527042195320E073-4356
chr174219534142195499E073-4177
chr174219578542195888E073-3788
chr174219600842196559E073-3117
chr174219656142196833E073-2843
chr174219717342197302E073-2374
chr174219755442197633E073-2043
chr174219766442197752E073-1924
chr174219778742197876E073-1800
chr174219804342198083E073-1593
chr174220195042202003E0732274
chr174224545442246279E07345778
chr174224732342248646E07347647
chr174215030042150497E074-49179
chr174215055342150613E074-49063
chr174215067442150760E074-48916
chr174215557042155639E074-44037
chr174215571142155812E074-43864
chr174215583642155876E074-43800
chr174215596742156045E074-43631
chr174217203842172088E074-27588
chr174217224442172326E074-27350
chr174217234142172391E074-27285
chr174217393142174023E074-25653
chr174217445742175844E074-23832
chr174217617042176220E074-23456
chr174217652442176638E074-23038
chr174217664942176737E074-22939
chr174217679242176842E074-22834
chr174217711242177193E074-22483
chr174217723342177333E074-22343
chr174217738642177605E074-22071
chr174218032442180872E074-18804
chr174218090142181021E074-18655
chr174218176042181950E074-17726
chr174218203442182258E074-17418
chr174218227842182377E074-17299
chr174218254042182605E074-17071
chr174218284642183809E074-15867
chr174218500842187352E074-12324
chr174218768542190742E074-8934
chr174219095842191117E074-8559
chr174219126842191343E074-8333
chr174219142142191522E074-8154
chr174219168342192136E074-7540
chr174219218742192270E074-7406
chr174219242542192485E074-7191
chr174219251942192569E074-7107
chr174219259242192709E074-6967
chr174219275942192940E074-6736
chr174219298342193419E074-6257
chr174219342142193533E074-6143
chr174219355342193689E074-5987
chr174219374342193803E074-5873
chr174219381042193860E074-5816
chr174219410042194150E074-5526
chr174219416342194213E074-5463
chr174219421442194354E074-5322
chr174219527042195320E074-4356
chr174219534142195499E074-4177
chr174219578542195888E074-3788
chr174219600842196559E074-3117
chr174219656142196833E074-2843
chr174219697142197159E074-2517
chr174219717342197302E074-2374
chr174219755442197633E074-2043
chr174219766442197752E074-1924
chr174219778742197876E074-1800
chr174219804342198083E074-1593
chr174219814242199476E074-200
chr174220195042202003E0742274
chr174221515842216398E07415482
chr174224519242245369E07445516
chr174224545442246279E07445778
chr174214976442149814E081-49862
chr174217125742171334E081-28342
chr174217203842172088E081-27588
chr174217224442172326E081-27350
chr174217234142172391E081-27285
chr174217393142174023E081-25653
chr174217445742175844E081-23832
chr174218500842187352E081-12324
chr174218768542190742E081-8934
chr174219095842191117E081-8559
chr174219126842191343E081-8333
chr174219142142191522E081-8154
chr174219168342192136E081-7540
chr174219342142193533E081-6143
chr174219355342193689E081-5987
chr174219374342193803E081-5873
chr174219527042195320E081-4356
chr174219534142195499E081-4177
chr174219578542195888E081-3788
chr174219600842196559E081-3117
chr174219656142196833E081-2843
chr174219697142197159E081-2517
chr174219717342197302E081-2374
chr174219755442197633E081-2043
chr174219778742197876E081-1800
chr174219804342198083E081-1593
chr174224545442246279E08145778
chr174224732342248646E08147647
chr174218203442182258E082-17418
chr174218227842182377E082-17299
chr174218254042182605E082-17071
chr174218284642183809E082-15867
chr174218500842187352E082-12324
chr174218768542190742E082-8934
chr174219242542192485E082-7191
chr174219251942192569E082-7107
chr174219259242192709E082-6967
chr174219275942192940E082-6736
chr174219298342193419E082-6257
chr174219342142193533E082-6143
chr174219355342193689E082-5987
chr174219374342193803E082-5873
chr174219381042193860E082-5816
chr174219410042194150E082-5526
chr174219416342194213E082-5463
chr174219421442194354E082-5322
chr174219457842195141E082-4535
chr174219527042195320E082-4356
chr174219534142195499E082-4177
chr174219578542195888E082-3788
chr174220195042202003E0822274
chr174224485342245034E08245177
chr174224505042245140E08245374
chr174224519242245369E08245516










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr174219954542201868E0670
chr174221900842220161E06719332
chr174219954542201868E0680
chr174221900842220161E06819332
chr174219954542201868E0690
chr174221900842220161E06919332
chr174219954542201868E0700
chr174221900842220161E07019332
chr174219954542201868E0710
chr174221900842220161E07119332
chr174219954542201868E0720
chr174221900842220161E07219332
chr174219954542201868E0730
chr174221900842220161E07319332
chr174219954542201868E0740
chr174221900842220161E07419332
chr174219954542201868E0810
chr174219954542201868E0820
chr174221900842220161E08219332