rs7963894

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
G==0068 (2057/29978,GnomAD)
G==0080 (2335/29118,TOPMED)
G==0092 (459/5008,1000G)
G==0077 (295/3854,ALSPAC)
G==0085 (314/3708,TWINSUK)
chr12:94741247 (GRCh38.p7) (12q22)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 12NC_000012.12:g.94741247G>A
GRCh37.p13 chr 12NC_000012.11:g.95135023G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.057A=0.943
1000GenomesAmericanSub694G=0.160A=0.840
1000GenomesEast AsianSub1008G=0.094A=0.906
1000GenomesEuropeSub1006G=0.048A=0.952
1000GenomesGlobalStudy-wide5008G=0.092A=0.908
1000GenomesSouth AsianSub978G=0.130A=0.870
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.077A=0.923
The Genome Aggregation DatabaseAfricanSub8724G=0.052A=0.948
The Genome Aggregation DatabaseAmericanSub838G=0.170A=0.830
The Genome Aggregation DatabaseEast AsianSub1622G=0.106A=0.894
The Genome Aggregation DatabaseEuropeSub18492G=0.068A=0.931
The Genome Aggregation DatabaseGlobalStudy-wide29978G=0.068A=0.931
The Genome Aggregation DatabaseOtherSub302G=0.030A=0.970
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.080A=0.919
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.085A=0.915
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs79638940.000769alcohol consumption (maxi-drinks)24277619

eQTL of rs7963894 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7963894 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr129509804395098100E067-36923
chr129509810395099409E067-35614
chr129512620695126477E067-8546
chr129512654895126660E067-8363
chr129516219695163219E06727173
chr129509810395099409E068-35614
chr129514768095147846E06812657
chr129516219695163219E06827173
chr129516367595163863E06828652
chr129516390695164080E06828883
chr129516419795164285E06829174
chr129516435195164391E06829328
chr129516446095164914E06829437
chr129516509595165289E06830072
chr129516567195165770E06830648
chr129517728095177486E06842257
chr129517750695178080E06842483
chr129509785095097932E069-37091
chr129509804395098100E069-36923
chr129512620695126477E069-8546
chr129512654895126660E069-8363
chr129512727095127320E069-7703
chr129516219695163219E06927173
chr129516367595163863E06928652
chr129516390695164080E06928883
chr129516419795164285E06929174
chr129516435195164391E06929328
chr129516446095164914E06929437
chr129516509595165289E06930072
chr129516567195165770E06930648
chr129510656695107218E070-27805
chr129511934695119903E070-15120
chr129512004695120747E070-14276
chr129512077595120881E070-14142
chr129512106695121172E070-13851
chr129512129095121413E070-13610
chr129512146795121568E070-13455
chr129516171495161794E07026691
chr129516183095161953E07026807
chr129516195795162094E07026934
chr129516219695163219E07027173
chr129516419795164285E07029174
chr129516435195164391E07029328
chr129516446095164914E07029437
chr129518431195184387E07049288
chr129518454995184599E07049526
chr129518469395184909E07049670
chr129509804395098100E071-36923
chr129512589495125988E071-9035
chr129512603095126157E071-8866
chr129512620695126477E071-8546
chr129512654895126660E071-8363
chr129512727095127320E071-7703
chr129514522595145303E07110202
chr129514682295147650E07111799
chr129514768095147846E07112657
chr129516195795162094E07126934
chr129516219695163219E07127173
chr129516367595163863E07128652
chr129516390695164080E07128883
chr129516419795164285E07129174
chr129516435195164391E07129328
chr129516446095164914E07129437
chr129516509595165289E07130072
chr129516567195165770E07130648
chr129511934695119903E072-15120
chr129509804395098100E073-36923
chr129509810395099409E073-35614
chr129512620695126477E073-8546
chr129512727095127320E073-7703
chr129516567195165770E07330648
chr129509485395094893E074-40130
chr129509810395099409E074-35614
chr129509942595099584E074-35439
chr129509959895099778E074-35245
chr129512620695126477E074-8546
chr129512654895126660E074-8363
chr129512727095127320E074-7703
chr129515683695156891E07421813
chr129516419795164285E07429174
chr129516435195164391E07429328
chr129516446095164914E07429437
chr129516509595165289E07430072
chr129516567195165770E07430648
chr129516632295166374E07431299
chr129509981195100050E081-34973
chr129511096495111124E081-23899
chr129511114195111194E081-23829
chr129514286395143102E0817840
chr129514316795143549E0818144
chr129514375495144032E0818731
chr129514428595144337E0819262
chr129514447795144539E0819454
chr129514455395144603E0819530
chr129514461295144731E0819589
chr129514630095146360E08111277
chr129514682295147650E08111799
chr129514768095147846E08112657
chr129516144995161499E08126426
chr129516171495161794E08126691
chr129516183095161953E08126807
chr129516195795162094E08126934
chr129516219695163219E08127173
chr129516367595163863E08128652
chr129516390695164080E08128883
chr129516419795164285E08129174
chr129516435195164391E08129328
chr129516446095164914E08129437
chr129516632295166374E08131299
chr129510804095108574E082-26449
chr129510861995108874E082-26149
chr129512004695120747E082-14276
chr129512077595120881E082-14142
chr129514682295147650E08211799
chr129514768095147846E08212657
chr129514802695148078E08213003
chr129516144995161499E08226426
chr129516171495161794E08226691
chr129516183095161953E08226807
chr129516195795162094E08226934
chr129516219695163219E08227173
chr129516367595163863E08228652
chr129516390695164080E08228883
chr129516419795164285E08229174