SNP Detail Info-rs79749241

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0047 (1417/29982,GnomAD)
A=0046 (1340/29118,TOPMED)
A=0099 (495/5008,1000G)
A=0047 (182/3854,ALSPAC)
A=0047 (174/3708,TWINSUK)

Position: chr8:75290351 (GRCh38.p7) (8q21.13)

Phenotype: CD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 2 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 8	NC_000008.11:g.75290351G>A
GRCh37.p13 chr 8	NC_000008.10:g.76202586G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.971	A=0.029
1000Genomes	American	Sub	694	G=0.950	A=0.050
1000Genomes	East Asian	Sub	1008	G=0.819	A=0.181
1000Genomes	Europe	Sub	1006	G=0.961	A=0.039
1000Genomes	Global	Study-wide	5008	G=0.901	A=0.099
1000Genomes	South Asian	Sub	978	G=0.790	A=0.210
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.953	A=0.047
The Genome Aggregation Database	African	Sub	8732	G=0.969	A=0.031
The Genome Aggregation Database	American	Sub	838	G=0.970	A=0.030
The Genome Aggregation Database	East Asian	Sub	1614	G=0.812	A=0.188
The Genome Aggregation Database	Europe	Sub	18496	G=0.957	A=0.042
The Genome Aggregation Database	Global	Study-wide	29982	G=0.952	A=0.047
The Genome Aggregation Database	Other	Sub	302	G=0.910	A=0.090
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.954	A=0.046
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.953	A=0.047

PMID	Title	Author	Journal
23958962	Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.	Gelernter J	Mol Psychiatry

SNP ID	p-value	Traits	Study
rs79749241	0.000117	cocaine dependence	23958962

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr8	76217812	76218095	E071	15226
chr8	76218299	76218349	E071	15713

rs79749241