rs7981680

Homo sapiens
C>G
FLT1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0177 (5325/29958,GnomAD)
G=0272 (7929/29116,TOPMED)
G=0208 (1043/5008,1000G)
G=0005 (19/3854,ALSPAC)
G=0005 (19/3708,TWINSUK)
chr13:28319733 (GRCh38.p7) (13q12.3)
AD
GWASdb2
1   publication(s)
See rs on genome
17 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.28319733C>G
GRCh37.p13 chr 13NC_000013.10:g.28893870C>G
FLT1 RefSeqGeneNG_012003.1:g.180396G>C

Gene: FLT1, fms related tyrosine kinase 1(minus strand)

Molecule type Change Amino acid[Codon] SO Term
FLT1 transcript variant 1NM_002019.4:c.N/AIntron Variant
FLT1 transcript variant 2NM_001159920.1:c.N/AGenic Downstream Transcript Variant
FLT1 transcript variant 3NM_001160030.1:c.N/AGenic Downstream Transcript Variant
FLT1 transcript variant 4NM_001160031.1:c.N/AGenic Downstream Transcript Variant
FLT1 transcript variant X1XM_017020485.1:c.N/AIntron Variant
FLT1 transcript variant X2XM_011535014.1:c.N/AGenic Downstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.305G=0.695
1000GenomesAmericanSub694C=0.950G=0.050
1000GenomesEast AsianSub1008C=0.943G=0.057
1000GenomesEuropeSub1006C=0.991G=0.009
1000GenomesGlobalStudy-wide5008C=0.792G=0.208
1000GenomesSouth AsianSub978C=0.980G=0.020
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.995G=0.005
The Genome Aggregation DatabaseAfricanSub8690C=0.413G=0.587
The Genome Aggregation DatabaseAmericanSub838C=0.950G=0.050
The Genome Aggregation DatabaseEast AsianSub1622C=0.932G=0.068
The Genome Aggregation DatabaseEuropeSub18506C=0.995G=0.004
The Genome Aggregation DatabaseGlobalStudy-wide29958C=0.822G=0.177
The Genome Aggregation DatabaseOtherSub302C=0.990G=0.010
Trans-Omics for Precision MedicineGlobalStudy-wide29116C=0.727G=0.272
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.995G=0.005
PMID Title Author Journal

P-Value

SNP ID p-value Traits Study
rs79816809.64E-13alcohol consumptionpha001400

eQTL of rs7981680 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7981680 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr132887400128874400E068-19470
chr132887345528873532E070-20338
chr132887400128874400E070-19470
chr132887451828874619E070-19251
chr132887464628874744E070-19126
chr132887478328874873E070-18997
chr132887511228875156E070-18714
chr132887548928875685E070-18185
chr132887400128874400E071-19470
chr132887451828874619E071-19251
chr132892835928928433E07134489
chr132893134428931985E07137474
chr132887400128874400E072-19470
chr132889810228899104E0744232
chr132887451828874619E081-19251
chr132887464628874744E081-19126
chr132887478328874873E081-18997