rs8006978

Homo sapiens
G>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0357 (10683/29896,GnomAD)
T=0313 (9130/29118,TOPMED)
T=0247 (1237/5008,1000G)
T=0419 (1616/3854,ALSPAC)
T=0415 (1537/3708,TWINSUK)
chr14:42164869 (GRCh38.p7) (14q21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.42164869G>T
GRCh37.p13 chr 14NC_000014.8:g.42634072G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.809T=0.191
1000GenomesAmericanSub694G=0.770T=0.230
1000GenomesEast AsianSub1008G=0.967T=0.033
1000GenomesEuropeSub1006G=0.557T=0.443
1000GenomesGlobalStudy-wide5008G=0.753T=0.247
1000GenomesSouth AsianSub978G=0.650T=0.350
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.581T=0.419
The Genome Aggregation DatabaseAfricanSub8708G=0.761T=0.239
The Genome Aggregation DatabaseAmericanSub838G=0.770T=0.230
The Genome Aggregation DatabaseEast AsianSub1612G=0.942T=0.058
The Genome Aggregation DatabaseEuropeSub18436G=0.556T=0.444
The Genome Aggregation DatabaseGlobalStudy-wide29896G=0.642T=0.357
The Genome Aggregation DatabaseOtherSub302G=0.570T=0.430
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.686T=0.313
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.585T=0.415
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs80069782.1E-05alcoholism (heaviness of drinking)21529783

eQTL of rs8006978 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs8006978 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.