rs8040009

Homo sapiens
T>C
C15orf32 : 3 Prime UTR Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0303 (9080/29920,GnomAD)
C=0372 (10847/29118,TOPMED)
C=0293 (1469/5008,1000G)
C=0202 (777/3854,ALSPAC)
C=0204 (757/3708,TWINSUK)
chr15:92501109 (GRCh38.p7) (15q26.1)
AD
GWASdb2 | GWASCatalog
4   publication(s)
See rs on genome
98 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.92501109T>C
GRCh37.p13 chr 15NC_000015.9:g.93044339T>C

Gene: C15orf32, chromosome 15 open reading frame 32(plus strand)

Molecule type Change Amino acid[Codon] SO Term
C15orf32 transcript variant 1NM_153040.2:c.N/A3 Prime UTR Variant
C15orf32 transcript variant 2NM_001301106.1:c.N/A3 Prime UTR Variant
C15orf32 transcript variant X1XM_011521257.2:c.N/AGenic Downstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.328C=0.672
1000GenomesAmericanSub694T=0.800C=0.200
1000GenomesEast AsianSub1008T=0.865C=0.135
1000GenomesEuropeSub1006T=0.812C=0.188
1000GenomesGlobalStudy-wide5008T=0.707C=0.293
1000GenomesSouth AsianSub978T=0.880C=0.120
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.798C=0.202
The Genome Aggregation DatabaseAfricanSub8692T=0.385C=0.615
The Genome Aggregation DatabaseAmericanSub836T=0.820C=0.180
The Genome Aggregation DatabaseEast AsianSub1612T=0.870C=0.130
The Genome Aggregation DatabaseEuropeSub18478T=0.819C=0.180
The Genome Aggregation DatabaseGlobalStudy-wide29920T=0.696C=0.303
The Genome Aggregation DatabaseOtherSub302T=0.840C=0.160
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.627C=0.372
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.796C=0.204
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry
20386566Genome-wide association study of bipolar I disorder in the Han Chinese population.Lee MTMol Psychiatry
21085053Database of genetic studies of bipolar disorder.Piletz JEPsychiatr Genet
22693595Identification of sialyltransferase 8B as a generalized susceptibility gene for psychotic and mood disorders on chromosome 15q25-26.McAuley EZPLoS One

P-Value

SNP ID p-value Traits Study
rs80400090.0000003alcoholism (heaviness of drinking)21529783
rs80400093.00E-07alcohol dependence21529783

eQTL of rs8040009 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs8040009 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr159303664993036699E067-7640
chr159303675893036947E067-7392
chr159303698393037084E067-7255
chr159306471393065498E06720374
chr159303664993036699E068-7640
chr159303675893036947E068-7392
chr159306311093063206E06818771
chr159306321593063284E06818876
chr159303543893036636E069-7703
chr159303664993036699E069-7640
chr159303675893036947E069-7392
chr159306471393065498E06920374
chr159301250393012611E070-31728
chr159301273793012787E070-31552
chr159301283793012897E070-31442
chr159303543893036636E070-7703
chr159303664993036699E070-7640
chr159303675893036947E070-7392
chr159303698393037084E070-7255
chr159303714693037196E070-7143
chr159303723593037292E070-7047
chr159303756793037944E070-6395
chr159303814093038947E070-5392
chr159303901493039064E070-5275
chr159304354693043732E070-607
chr159304374093043985E070-354
chr159306815093068239E07023811
chr159306826093068438E07023921
chr159306847393068881E07024134
chr159306888393069066E07024544
chr159307989993080342E07035560
chr159303543893036636E071-7703
chr159303664993036699E071-7640
chr159303675893036947E071-7392
chr159303698393037084E071-7255
chr159303814093038947E071-5392
chr159306311093063206E07118771
chr159306321593063284E07118876
chr159306471393065498E07120374
chr159303901493039064E072-5275
chr159306471393065498E07220374
chr159303664993036699E073-7640
chr159303675893036947E073-7392
chr159299785192998197E081-46142
chr159299833992998390E081-45949
chr159299949492999603E081-44736
chr159299977192999821E081-44518
chr159300010093000160E081-44179
chr159300039893000466E081-43873
chr159300047193000525E081-43814
chr159300073193001471E081-42868
chr159301680893016858E081-27481
chr159301716493017465E081-26874
chr159301751493017603E081-26736
chr159301777093017824E081-26515
chr159303468493034744E081-9595
chr159303477493034904E081-9435
chr159303494693035119E081-9220
chr159303513493035184E081-9155
chr159303543893036636E081-7703
chr159303664993036699E081-7640
chr159303675893036947E081-7392
chr159303698393037084E081-7255
chr159303714693037196E081-7143
chr159303723593037292E081-7047
chr159303756793037944E081-6395
chr159303814093038947E081-5392
chr159303901493039064E081-5275
chr159304354693043732E081-607
chr159304374093043985E081-354
chr159304726693047359E0812927
chr159308433993085062E08140000
chr159299785192998197E082-46142
chr159299833992998390E082-45949
chr159299857492998711E082-45628
chr159299873392998829E082-45510
chr159299949492999603E082-44736
chr159299977192999821E082-44518
chr159300010093000160E082-44179
chr159300039893000466E082-43873
chr159301716493017465E082-26874
chr159301751493017603E082-26736
chr159301777093017824E082-26515
chr159303477493034904E082-9435
chr159303494693035119E082-9220
chr159303513493035184E082-9155
chr159303543893036636E082-7703
chr159303664993036699E082-7640
chr159303675893036947E082-7392
chr159303698393037084E082-7255
chr159303714693037196E082-7143
chr159303723593037292E082-7047
chr159303756793037944E082-6395
chr159303814093038947E082-5392
chr159303901493039064E082-5275
chr159304354693043732E082-607
chr159304374093043985E082-354
chr159304835793048411E0824018