rs804753

Homo sapiens
T>C / T>G
None
Check p-value
SNV (Single Nucleotide Variation)
T==0107 (3230/29958,GnomAD)
T==0128 (3745/29118,TOPMED)
T==0173 (865/5008,1000G)
T==0071 (273/3854,ALSPAC)
T==0059 (220/3708,TWINSUK)
chr7:52552937 (GRCh38.p7) (7p12.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.52552937T>C
GRCh38.p7 chr 7NC_000007.14:g.52552937T>G
GRCh37.p13 chr 7NC_000007.13:g.52620633T>C
GRCh37.p13 chr 7NC_000007.13:g.52620633T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.188C=0.812
1000GenomesAmericanSub694T=0.080C=0.920
1000GenomesEast AsianSub1008T=0.283C=0.717
1000GenomesEuropeSub1006T=0.073C=0.927
1000GenomesGlobalStudy-wide5008T=0.173C=0.827
1000GenomesSouth AsianSub978T=0.210C=0.790
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.071C=0.929
The Genome Aggregation DatabaseAfricanSub8722T=0.199C=0.801
The Genome Aggregation DatabaseAmericanSub836T=0.070C=0.930
The Genome Aggregation DatabaseEast AsianSub1614T=0.264C=0.736
The Genome Aggregation DatabaseEuropeSub18484T=0.053C=0.946
The Genome Aggregation DatabaseGlobalStudy-wide29958T=0.107C=0.892
The Genome Aggregation DatabaseOtherSub302T=0.070C=0.930
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.128C=0.871
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.059C=0.941
PMID Title Author Journal
21703634A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.Wang KSJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs8047534.89E-05alcohol dependence21703634

eQTL of rs804753 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs804753 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.