SNP Detail Info-rs8058542

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G==0385 (11531/29898,GnomAD)
G==0463 (13501/29118,TOPMED)
G==0384 (1924/5008,1000G)
G==0265 (1022/3854,ALSPAC)
G==0256 (949/3708,TWINSUK)

Position: chr16:7804982 (GRCh38.p7) (16p13.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 12 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 16	NC_000016.10:g.7804982G>A
GRCh37.p13 chr 16	NC_000016.9:g.7854984G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.813	A=0.187
1000Genomes	American	Sub	694	G=0.220	A=0.780
1000Genomes	East Asian	Sub	1008	G=0.167	A=0.833
1000Genomes	Europe	Sub	1006	G=0.232	A=0.768
1000Genomes	Global	Study-wide	5008	G=0.384	A=0.616
1000Genomes	South Asian	Sub	978	G=0.300	A=0.700
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.265	A=0.735
The Genome Aggregation Database	African	Sub	8680	G=0.749	A=0.251
The Genome Aggregation Database	American	Sub	834	G=0.190	A=0.810
The Genome Aggregation Database	East Asian	Sub	1614	G=0.178	A=0.822
The Genome Aggregation Database	Europe	Sub	18470	G=0.244	A=0.755
The Genome Aggregation Database	Global	Study-wide	29898	G=0.385	A=0.614
The Genome Aggregation Database	Other	Sub	300	G=0.220	A=0.780
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.463	A=0.536
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.256	A=0.744

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs8058542	0.00068	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr16	7805686	7805786	E070	-49198
chr16	7892941	7893823	E070	37957
chr16	7894024	7894161	E070	39040
chr16	7894215	7894265	E070	39231
chr16	7894814	7894864	E070	39830
chr16	7836536	7836658	E081	-18326
chr16	7836923	7837101	E081	-17883
chr16	7892941	7893823	E081	37957
chr16	7894024	7894161	E081	39040
chr16	7899519	7899669	E081	44535
chr16	7892941	7893823	E082	37957
chr16	7894814	7894864	E082	39830

rs8058542