rs8071366

Homo sapiens
G>A
LOC105371874 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0217 (6518/29920,GnomAD)
A=0226 (6582/29118,TOPMED)
A=0232 (1163/5008,1000G)
A=0209 (806/3854,ALSPAC)
A=0201 (744/3708,TWINSUK)
chr17:68829799 (GRCh38.p7) (17q24.2)
AD
GWASdb2
1   publication(s)
See rs on genome
121 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 17NC_000017.11:g.68829799G>A
GRCh37.p13 chr 17NC_000017.10:g.66825940G>A

Gene: LOC105371874, uncharacterized LOC105371874(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105371874 transcript variant X1XR_001752986.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.702A=0.298
1000GenomesAmericanSub694G=0.760A=0.240
1000GenomesEast AsianSub1008G=0.714A=0.286
1000GenomesEuropeSub1006G=0.798A=0.202
1000GenomesGlobalStudy-wide5008G=0.768A=0.232
1000GenomesSouth AsianSub978G=0.890A=0.110
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.791A=0.209
The Genome Aggregation DatabaseAfricanSub8706G=0.739A=0.261
The Genome Aggregation DatabaseAmericanSub834G=0.790A=0.210
The Genome Aggregation DatabaseEast AsianSub1618G=0.726A=0.274
The Genome Aggregation DatabaseEuropeSub18460G=0.807A=0.192
The Genome Aggregation DatabaseGlobalStudy-wide29920G=0.782A=0.217
The Genome Aggregation DatabaseOtherSub302G=0.760A=0.240
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.774A=0.226
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.799A=0.201
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs80713660.000868alcohol dependence20201924

eQTL of rs8071366 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs8071366 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr176677989266780594E067-45346
chr176678905866789665E067-36275
chr176678979266790407E067-35533
chr176679067766791563E067-34377
chr176681564666815933E067-10007
chr176685779266858017E06731852
chr176685816866858322E06732228
chr176677989266780594E068-45346
chr176678062566780809E068-45131
chr176678786066788790E068-37150
chr176678879966788889E068-37051
chr176678894066789051E068-36889
chr176678905866789665E068-36275
chr176678979266790407E068-35533
chr176679962566799891E068-26049
chr176679990766800011E068-25929
chr176681564666815933E068-10007
chr176681627266816316E068-9624
chr176681661166816668E068-9272
chr176681673166816912E068-9028
chr176681696166817808E068-8132
chr176685741366857463E06831473
chr176685779266858017E06831852
chr176678786066788790E069-37150
chr176678879966788889E069-37051
chr176678894066789051E069-36889
chr176678905866789665E069-36275
chr176678979266790407E069-35533
chr176679962566799891E069-26049
chr176679990766800011E069-25929
chr176681467566814859E069-11081
chr176681492266815015E069-10925
chr176681564666815933E069-10007
chr176681627266816316E069-9624
chr176681696166817808E069-8132
chr176681789266818782E069-7158
chr176683605966836145E06910119
chr176683628266836503E06910342
chr176683663566836685E06910695
chr176685741366857463E06931473
chr176685779266858017E06931852
chr176685816866858322E06932228
chr176686470366864815E06938763
chr176686497466865162E06939034
chr176677667966777024E071-48916
chr176677989266780594E071-45346
chr176678062566780809E071-45131
chr176678786066788790E071-37150
chr176678879966788889E071-37051
chr176678894066789051E071-36889
chr176678905866789665E071-36275
chr176678979266790407E071-35533
chr176679067766791563E071-34377
chr176679334566793493E071-32447
chr176679374366793787E071-32153
chr176679941166799517E071-26423
chr176679962566799891E071-26049
chr176679990766800011E071-25929
chr176681467566814859E071-11081
chr176681492266815015E071-10925
chr176681627266816316E071-9624
chr176681661166816668E071-9272
chr176681673166816912E071-9028
chr176681696166817808E071-8132
chr176681789266818782E071-7158
chr176683605966836145E07110119
chr176683628266836503E07110342
chr176683663566836685E07110695
chr176685741366857463E07131473
chr176686470366864815E07138763
chr176686497466865162E07139034
chr176677989266780594E072-45346
chr176678786066788790E072-37150
chr176678879966788889E072-37051
chr176678894066789051E072-36889
chr176678905866789665E072-36275
chr176678979266790407E072-35533
chr176679067766791563E072-34377
chr176681467566814859E072-11081
chr176681492266815015E072-10925
chr176681564666815933E072-10007
chr176681627266816316E072-9624
chr176681661166816668E072-9272
chr176681673166816912E072-9028
chr176681696166817808E072-8132
chr176683605966836145E07210119
chr176683628266836503E07210342
chr176683963766840092E07213697
chr176685779266858017E07231852
chr176685816866858322E07232228
chr176686497466865162E07239034
chr176677989266780594E073-45346
chr176678905866789665E073-36275
chr176677970066779883E074-46057
chr176677989266780594E074-45346
chr176678062566780809E074-45131
chr176678786066788790E074-37150
chr176678879966788889E074-37051
chr176678894066789051E074-36889
chr176678905866789665E074-36275
chr176678979266790407E074-35533
chr176679067766791563E074-34377
chr176681492266815015E074-10925
chr176681564666815933E074-10007
chr176681661166816668E074-9272
chr176681673166816912E074-9028
chr176681696166817808E074-8132
chr176681789266818782E074-7158
chr176685779266858017E07431852
chr176685816866858322E07432228
chr176679941166799517E081-26423
chr176679962566799891E081-26049
chr176679990766800011E081-25929
chr176680112166801161E081-24779
chr176680124066801752E081-24188
chr176680186166802056E081-23884
chr176680267366802733E081-23207
chr176680329866803404E081-22536
chr176680353466803879E081-22061
chr176680543566805522E081-20418
chr176680562666805738E081-20202