rs8076501

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
G==0308 (9215/29838,GnomAD)
G==0270 (7875/29118,TOPMED)
G==0257 (1286/5008,1000G)
G==0420 (1618/3854,ALSPAC)
G==0408 (1513/3708,TWINSUK)
chr17:13291872 (GRCh38.p7) (17p12)
AD
GWASdb2
1   publication(s)
See rs on genome
4 Enhancers around
2 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 17NC_000017.11:g.13291872G>A
GRCh37.p13 chr 17NC_000017.10:g.13195189G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.031A=0.969
1000GenomesAmericanSub694G=0.370A=0.630
1000GenomesEast AsianSub1008G=0.192A=0.808
1000GenomesEuropeSub1006G=0.449A=0.551
1000GenomesGlobalStudy-wide5008G=0.257A=0.743
1000GenomesSouth AsianSub978G=0.350A=0.650
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.420A=0.580
The Genome Aggregation DatabaseAfricanSub8716G=0.094A=0.906
The Genome Aggregation DatabaseAmericanSub838G=0.320A=0.680
The Genome Aggregation DatabaseEast AsianSub1612G=0.199A=0.801
The Genome Aggregation DatabaseEuropeSub18370G=0.418A=0.581
The Genome Aggregation DatabaseGlobalStudy-wide29838G=0.308A=0.691
The Genome Aggregation DatabaseOtherSub302G=0.390A=0.610
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.270A=0.729
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.408A=0.592
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs80765010.00022alcohol dependence(early age of onset)20201924
rs80765010.0007alcohol dependence20201924

eQTL of rs8076501 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs8076501 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr171321504113215147E07019852
chr171321518113215261E07019992
chr171321621113216299E07021022
chr171324086813240928E07045679

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr171324107313241768E06945884
chr171324107313241768E07145884