rs8081614

Homo sapiens
T>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0225 (6745/29900,GnomAD)
G=0237 (6927/29118,TOPMED)
G=0310 (1553/5008,1000G)
G=0191 (738/3854,ALSPAC)
G=0186 (690/3708,TWINSUK)
chr17:66288266 (GRCh38.p7) (17q24.2)
AD
GWASdb2
1   publication(s)
See rs on genome
100 Enhancers around
27 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 17NC_000017.11:g.66288266T>G
GRCh37.p13 chr 17NC_000017.10:g.64284384T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.703G=0.297
1000GenomesAmericanSub694T=0.670G=0.330
1000GenomesEast AsianSub1008T=0.785G=0.215
1000GenomesEuropeSub1006T=0.809G=0.191
1000GenomesGlobalStudy-wide5008T=0.690G=0.310
1000GenomesSouth AsianSub978T=0.470G=0.530
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.809G=0.191
The Genome Aggregation DatabaseAfricanSub8698T=0.713G=0.287
The Genome Aggregation DatabaseAmericanSub834T=0.680G=0.320
The Genome Aggregation DatabaseEast AsianSub1612T=0.811G=0.189
The Genome Aggregation DatabaseEuropeSub18454T=0.803G=0.196
The Genome Aggregation DatabaseGlobalStudy-wide29900T=0.774G=0.225
The Genome Aggregation DatabaseOtherSub302T=0.830G=0.170
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.762G=0.237
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.814G=0.186
PMID Title Author Journal
22096494A novel, functional and replicable risk gene region for alcohol dependence identified by genome-wide association study.Zuo LPLoS One

P-Value

SNP ID p-value Traits Study
rs80816149.3E-05alcohol dependence22096494

eQTL of rs8081614 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs8081614 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr176430201864302068E06717634
chr176430214364302187E06717759
chr176430220464303064E06717820
chr176430508864305211E06720704
chr176430521764305347E06720833
chr176430562364305913E06721239
chr176430593064306237E06721546
chr176430645864306572E06722074
chr176430685264306957E06722468
chr176430707864307143E06722694
chr176430719764307247E06722813
chr176432569564325739E06741311
chr176424247664242944E068-41440
chr176424488764244937E068-39447
chr176430201864302068E06817634
chr176430214364302187E06817759
chr176430220464303064E06817820
chr176430508864305211E06820704
chr176430521764305347E06820833
chr176430562364305913E06821239
chr176430593064306237E06821546
chr176430645864306572E06822074
chr176430685264306957E06822468
chr176432529064325440E06840906
chr176432551564325592E06841131
chr176432569564325739E06841311
chr176433415564334271E06849771
chr176425111564251998E069-32386
chr176430220464303064E06917820
chr176430344764303508E06919063
chr176430508864305211E06920704
chr176430521764305347E06920833
chr176430562364305913E06921239
chr176430593064306237E06921546
chr176432569564325739E06941311
chr176425342864253478E070-30906
chr176425364464253694E070-30690
chr176428983364289883E0705449
chr176428992464289995E0705540
chr176429650364296639E07012119
chr176429670764296764E07012323
chr176429680264296885E07012418
chr176429690264296960E07012518
chr176430508864305211E07020704
chr176430521764305347E07020833
chr176430562364305913E07021239
chr176430593064306237E07021546
chr176430645864306572E07022074
chr176430963564309737E07025251
chr176430979064309840E07025406
chr176431018964310283E07025805
chr176431032864310378E07025944
chr176429680264296885E07112418
chr176429690264296960E07112518
chr176429700764297067E07112623
chr176429707664297116E07112692
chr176429711764297533E07112733
chr176430220464303064E07117820
chr176430508864305211E07120704
chr176430521764305347E07120833
chr176430562364305913E07121239
chr176430593064306237E07121546
chr176430645864306572E07122074
chr176432456364324640E07140179
chr176432500464325060E07140620
chr176433415564334271E07149771
chr176430201864302068E07217634
chr176430214364302187E07217759
chr176430220464303064E07217820
chr176430508864305211E07220704
chr176430521764305347E07220833
chr176430562364305913E07221239
chr176430593064306237E07221546
chr176430645864306572E07222074
chr176430685264306957E07222468
chr176430508864305211E07320704
chr176430521764305347E07320833
chr176430562364305913E07321239
chr176430593064306237E07321546
chr176430645864306572E07322074
chr176432500464325060E07340620
chr176432529064325440E07340906
chr176424247664242944E074-41440
chr176430201864302068E07417634
chr176430214364302187E07417759
chr176430220464303064E07417820
chr176430508864305211E07420704
chr176430521764305347E07420833
chr176430562364305913E07421239
chr176430593064306237E07421546
chr176430645864306572E07422074
chr176430685264306957E07422468
chr176432551564325592E07441131
chr176433415564334271E07449771
chr176429700764297067E08112623
chr176429707664297116E08112692
chr176429711764297533E08112733
chr176433415564334271E08149771
chr176426858764269744E082-14640
chr176426993964269989E082-14395










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr176429753864299868E06713154
chr176430015964300376E06715775
chr176430142164301797E06717037
chr176429753864299868E06813154
chr176430015964300376E06815775
chr176430142164301797E06817037
chr176429753864299868E06913154
chr176430015964300376E06915775
chr176430142164301797E06917037
chr176429753864299868E07013154
chr176430015964300376E07015775
chr176430142164301797E07017037
chr176429753864299868E07113154
chr176430015964300376E07115775
chr176430142164301797E07117037
chr176429753864299868E07213154
chr176430015964300376E07215775
chr176430142164301797E07217037
chr176429753864299868E07313154
chr176430015964300376E07315775
chr176430142164301797E07317037
chr176429753864299868E07413154
chr176430015964300376E07415775
chr176430142164301797E07417037
chr176429753864299868E08213154
chr176430015964300376E08215775
chr176430142164301797E08217037