rs8082305

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0158 (4726/29798,GnomAD)
A=0152 (4443/29118,TOPMED)
A=0136 (681/5008,1000G)
A=0153 (591/3854,ALSPAC)
A=0145 (536/3708,TWINSUK)
chr17:31779568 (GRCh38.p7) (17q11.2)
ND
GWASdb2
1   publication(s)
See rs on genome
37 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 17NC_000017.11:g.31779568G>A
GRCh37.p13 chr 17NC_000017.10:g.30106587G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.806A=0.194
1000GenomesAmericanSub694G=0.910A=0.090
1000GenomesEast AsianSub1008G=0.860A=0.140
1000GenomesEuropeSub1006G=0.846A=0.154
1000GenomesGlobalStudy-wide5008G=0.864A=0.136
1000GenomesSouth AsianSub978G=0.930A=0.070
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.847A=0.153
The Genome Aggregation DatabaseAfricanSub8604G=0.830A=0.170
The Genome Aggregation DatabaseAmericanSub836G=0.930A=0.070
The Genome Aggregation DatabaseEast AsianSub1604G=0.834A=0.166
The Genome Aggregation DatabaseEuropeSub18452G=0.843A=0.156
The Genome Aggregation DatabaseGlobalStudy-wide29798G=0.841A=0.158
The Genome Aggregation DatabaseOtherSub302G=0.840A=0.160
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.847A=0.152
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.855A=0.145
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs80823057.77E-05nicotine smoking19268276

eQTL of rs8082305 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs8082305 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr173007082030071420E067-35167
chr173007143830072124E067-34463
chr173007082030071420E068-35167
chr173007082030071420E069-35167
chr173007143830072124E069-34463
chr173007303330073644E069-32943
chr173006561530065786E071-40801
chr173007082030071420E071-35167
chr173007143830072124E071-34463
chr173007303330073644E071-32943
chr173013793730138062E07131350
chr173006561530065786E072-40801
chr173006585630065948E072-40639
chr173007082030071420E072-35167
chr173007143830072124E072-34463
chr173007082030071420E073-35167
chr173007143830072124E073-34463
chr173007082030071420E074-35167
chr173007143830072124E074-34463
chr173005955630059606E081-46981
chr173005967630059716E081-46871
chr173006049030060636E081-45951
chr173007082030071420E081-35167
chr173007143830072124E081-34463
chr173007262030072698E081-33889
chr173007275730072925E081-33662
chr173007303330073644E081-32943
chr173007370330073900E081-32687
chr173007393030074013E081-32574
chr173007424730074461E081-32126
chr173007446430074544E081-32043
chr173007654730076597E081-29990
chr173007672730076767E081-29820
chr173007678530076835E081-29752
chr173007143830072124E082-34463
chr173007303330073644E082-32943
chr173007370330073900E082-32687