rs8085261

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
A==0321 (9605/29876,GnomAD)
A==0323 (9418/29118,TOPMED)
A==0342 (1712/5008,1000G)
A==0330 (1273/3854,ALSPAC)
A==0323 (1199/3708,TWINSUK)
chr18:30531220 (GRCh38.p7) (18q12.1)
ND
GWASdb2
1   publication(s)
See rs on genome
17 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.30531220A>C
GRCh37.p13 chr 18NC_000018.9:g.28111186A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.322C=0.678
1000GenomesAmericanSub694A=0.310C=0.690
1000GenomesEast AsianSub1008A=0.392C=0.608
1000GenomesEuropeSub1006A=0.367C=0.633
1000GenomesGlobalStudy-wide5008A=0.342C=0.658
1000GenomesSouth AsianSub978A=0.310C=0.690
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.330C=0.670
The Genome Aggregation DatabaseAfricanSub8692A=0.328C=0.672
The Genome Aggregation DatabaseAmericanSub828A=0.250C=0.750
The Genome Aggregation DatabaseEast AsianSub1600A=0.366C=0.634
The Genome Aggregation DatabaseEuropeSub18454A=0.316C=0.683
The Genome Aggregation DatabaseGlobalStudy-wide29876A=0.321C=0.678
The Genome Aggregation DatabaseOtherSub302A=0.400C=0.600
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.323C=0.676
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.323C=0.677
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs80852613.15E-06alcohol and nictotine co-dependence20158304

eQTL of rs8085261 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs8085261 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr182810727028107515E069-3671
chr182810727028107515E071-3671
chr182810757828107628E071-3558
chr182812690628127123E07115720
chr182812727328127323E07116087
chr182809318228093232E072-17954
chr182809328828093450E072-17736
chr182810682628106992E072-4194
chr182810727028107515E072-3671
chr182810757828107628E072-3558
chr182812690628127123E07215720
chr182812727328127323E07216087
chr182812752628127634E07216340
chr182810682628106992E074-4194
chr182810727028107515E074-3671
chr182812690628127123E07415720
chr182812727328127323E07416087