rs8099869

Homo sapiens
C>T
ZNF225 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C==0326 (9759/29938,GnomAD)
C==0396 (11555/29118,TOPMED)
C==0445 (2227/5008,1000G)
C==0151 (581/3854,ALSPAC)
C==0159 (588/3708,TWINSUK)
chr19:44119223 (GRCh38.p7) (19q13.31)
AD
GWASdb2
1   publication(s)
See rs on genome
29 Enhancers around
80 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 19NC_000019.10:g.44119223C>T
GRCh37.p13 chr 19NC_000019.9:g.44623376C>T

Gene: ZNF225, zinc finger protein 225(plus strand)

Molecule type Change Amino acid[Codon] SO Term
ZNF225 transcript variant 2NM_001321685.1:c.N/AIntron Variant
ZNF225 transcript variant 1NM_013362.3:c.N/AIntron Variant
ZNF225 transcript variant X1XM_011527285.2:c.N/AIntron Variant
ZNF225 transcript variant X2XM_011527286.2:c.N/AIntron Variant
ZNF225 transcript variant X3XM_005259223.3:c.N/AGenic Upstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.693T=0.307
1000GenomesAmericanSub694C=0.460T=0.540
1000GenomesEast AsianSub1008C=0.501T=0.499
1000GenomesEuropeSub1006C=0.176T=0.824
1000GenomesGlobalStudy-wide5008C=0.445T=0.555
1000GenomesSouth AsianSub978C=0.310T=0.690
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.151T=0.849
The Genome Aggregation DatabaseAfricanSub8710C=0.608T=0.392
The Genome Aggregation DatabaseAmericanSub836C=0.480T=0.520
The Genome Aggregation DatabaseEast AsianSub1614C=0.459T=0.541
The Genome Aggregation DatabaseEuropeSub18476C=0.176T=0.823
The Genome Aggregation DatabaseGlobalStudy-wide29938C=0.326T=0.674
The Genome Aggregation DatabaseOtherSub302C=0.170T=0.830
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.396T=0.603
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.159T=0.841
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs80998690.000104alcohol consumption23743675

eQTL of rs8099869 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs8099869 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr194467075844670818E06747382
chr194467093344671011E06747557
chr194467104944671115E06747673
chr194461888344619034E068-4342
chr194467075844670818E06847382
chr194467093344671011E06847557
chr194460014844600194E069-23182
chr194460014844600194E070-23182
chr194461888344619034E070-4342
chr194461903744619091E070-4285
chr194461912544619165E070-4211
chr194467075844670818E07047382
chr194467093344671011E07047557
chr194467104944671115E07047673
chr194467187644671938E07048500
chr194461888344619034E071-4342
chr194467075844670818E07147382
chr194467075844670818E07247382
chr194467093344671011E07247557
chr194467075844670818E07447382
chr194467093344671011E07447557
chr194467187644671938E07448500
chr194467075844670818E08147382
chr194467093344671011E08147557
chr194467104944671115E08147673
chr194467187644671938E08148500
chr194460081644600930E082-22446
chr194467093344671011E08247557
chr194467104944671115E08247673









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr194457541944575610E067-47766
chr194457564244577153E067-46223
chr194459804744599722E067-23654
chr194461592544616789E067-6587
chr194461680644618482E067-4894
chr194464488144646741E06721505
chr194466849844670041E06745122
chr194457541944575610E068-47766
chr194457564244577153E068-46223
chr194459781244597885E068-25491
chr194459793544597989E068-25387
chr194459804744599722E068-23654
chr194461578744615827E068-7549
chr194461592544616789E068-6587
chr194461680644618482E068-4894
chr194464474344644803E06821367
chr194464488144646741E06821505
chr194466849844670041E06845122
chr194457541944575610E069-47766
chr194457564244577153E069-46223
chr194459804744599722E069-23654
chr194461578744615827E069-7549
chr194461592544616789E069-6587
chr194461680644618482E069-4894
chr194464488144646741E06921505
chr194466849844670041E06945122
chr194457541944575610E070-47766
chr194457564244577153E070-46223
chr194459804744599722E070-23654
chr194461592544616789E070-6587
chr194461680644618482E070-4894
chr194464474344644803E07021367
chr194464488144646741E07021505
chr194466849844670041E07045122
chr194457541944575610E071-47766
chr194457564244577153E071-46223
chr194459804744599722E071-23654
chr194461578744615827E071-7549
chr194461592544616789E071-6587
chr194461680644618482E071-4894
chr194464474344644803E07121367
chr194464488144646741E07121505
chr194466849844670041E07145122
chr194457541944575610E072-47766
chr194457564244577153E072-46223
chr194459804744599722E072-23654
chr194461592544616789E072-6587
chr194461680644618482E072-4894
chr194464474344644803E07221367
chr194464488144646741E07221505
chr194466849844670041E07245122
chr194457541944575610E073-47766
chr194457564244577153E073-46223
chr194459804744599722E073-23654
chr194461592544616789E073-6587
chr194461680644618482E073-4894
chr194464488144646741E07321505
chr194466849844670041E07345122
chr194457541944575610E074-47766
chr194457564244577153E074-46223
chr194459804744599722E074-23654
chr194461592544616789E074-6587
chr194461680644618482E074-4894
chr194464488144646741E07421505
chr194466849844670041E07445122
chr194457541944575610E081-47766
chr194457564244577153E081-46223
chr194459804744599722E081-23654
chr194461592544616789E081-6587
chr194461680644618482E081-4894
chr194464488144646741E08121505
chr194466849844670041E08145122
chr194457541944575610E082-47766
chr194457564244577153E082-46223
chr194459804744599722E082-23654
chr194461592544616789E082-6587
chr194461680644618482E082-4894
chr194464474344644803E08221367
chr194464488144646741E08221505
chr194466849844670041E08245122