| Sequence Name | Change(s) |
|---|---|
| GRCh38.p7 chr 19 | NC_000019.10:g.27912644A>G |
| GRCh37.p13 chr 19 | NC_000019.9:g.28403552A>G |
| Study | Population | Group | Sample # | Ref Allele | Alt Allele |
|---|---|---|---|---|---|
| 1000Genomes | African | Sub | 1322 | A=0.786 | G=0.214 |
| 1000Genomes | American | Sub | 694 | A=0.580 | G=0.420 |
| 1000Genomes | East Asian | Sub | 1008 | A=0.455 | G=0.545 |
| 1000Genomes | Europe | Sub | 1006 | A=0.618 | G=0.382 |
| 1000Genomes | Global | Study-wide | 5008 | A=0.622 | G=0.378 |
| 1000Genomes | South Asian | Sub | 978 | A=0.610 | G=0.390 |
| The Avon Longitudinal Study of Parents and Children | PARENT AND CHILD COHORT | Study-wide | 3854 | A=0.616 | G=0.384 |
| The Genome Aggregation Database | African | Sub | 8720 | A=0.760 | G=0.240 |
| The Genome Aggregation Database | American | Sub | 836 | A=0.540 | G=0.460 |
| The Genome Aggregation Database | East Asian | Sub | 1620 | A=0.425 | G=0.575 |
| The Genome Aggregation Database | Europe | Sub | 18474 | A=0.609 | G=0.391 |
| The Genome Aggregation Database | Global | Study-wide | 29952 | A=0.641 | G=0.358 |
| The Genome Aggregation Database | Other | Sub | 302 | A=0.620 | G=0.380 |
| Trans-Omics for Precision Medicine | Global | Study-wide | 29118 | A=0.688 | G=0.311 |
| UK 10K study - Twins | TWIN COHORT | Study-wide | 3708 | A=0.606 | G=0.394 |
| PMID | Title | Author | Journal |
|---|---|---|---|
| 24277619 | ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample. | Quillen EE | Am J Med Genet B Neuropsychiatr Genet |
| SNP ID | p-value | Traits | Study |
|---|---|---|---|
| rs811029 | 0.000225 | alcohol consumption (maxi-drinks) | 24277619 |
| Position (v37) | eGene | GeneID | Variant | p-value | TSS | Tissue |
|---|---|---|---|---|---|---|
| Chr19:28403552 | CTC-459F4.6 | ENSG00000267264.1 | A>G | 1.9152e-8 | 109106 | Cerebellum |
| Chr19:28403552 | AC022153.1 | ENSG00000267623.2 | A>G | 2.5001e-3 | 10049 | Cerebellar_Hemisphere |
| Probe ID | Position | Gene | beta | p-value | |||
|---|---|---|---|---|---|---|---|
| There is no meQTL annotation for this SNP | |||||||
There is no significant Hi-C chromatin interaction data for this SNP.
| Chromosome | Start | End | Region | Distance ( -/+ : Up/Downstream ) |
|---|---|---|---|---|
| chr19 | 28395906 | 28395983 | E067 | -7569 |
| chr19 | 28396238 | 28396327 | E067 | -7225 |
| chr19 | 28396600 | 28397548 | E067 | -6004 |
| chr19 | 28395906 | 28395983 | E068 | -7569 |
| chr19 | 28396238 | 28396327 | E068 | -7225 |
| chr19 | 28396600 | 28397548 | E068 | -6004 |
| chr19 | 28396600 | 28397548 | E069 | -6004 |
| chr19 | 28395906 | 28395983 | E071 | -7569 |
| chr19 | 28396238 | 28396327 | E071 | -7225 |
| chr19 | 28396600 | 28397548 | E071 | -6004 |
| chr19 | 28396238 | 28396327 | E072 | -7225 |
| chr19 | 28396600 | 28397548 | E072 | -6004 |
| chr19 | 28396238 | 28396327 | E073 | -7225 |
| chr19 | 28396238 | 28396327 | E074 | -7225 |
| chr19 | 28396600 | 28397548 | E074 | -6004 |
| chr19 | 28446320 | 28446447 | E081 | 42768 |
| chr19 | 28446522 | 28446797 | E081 | 42970 |