rs8128956

Homo sapiens
T>A / T>C
None
Check p-value
SNV (Single Nucleotide Variation)
A=0143 (4190/29118,TOPMED)
A=0127 (3470/27286,GnomAD)
A=0095 (478/5008,1000G)
A=0043 (164/3854,ALSPAC)
A=0040 (149/3708,TWINSUK)
chr21:31649104 (GRCh38.p7) (21q22.11)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 21NC_000021.9:g.31649104T>A
GRCh38.p7 chr 21NC_000021.9:g.31649104T>C
GRCh37.p13 chr 21NC_000021.8:g.33021417T>A
GRCh37.p13 chr 21NC_000021.8:g.33021417T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.708A=0.292
1000GenomesAmericanSub694T=0.960A=0.040
1000GenomesEast AsianSub1008T=0.997A=0.003
1000GenomesEuropeSub1006T=0.942A=0.058
1000GenomesGlobalStudy-wide5008T=0.905A=0.095
1000GenomesSouth AsianSub978T=0.990A=0.010
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.957A=0.043
The Genome Aggregation DatabaseAfricanSub8268T=0.716C=0.000
The Genome Aggregation DatabaseAmericanSub664T=0.970C=0.00,
The Genome Aggregation DatabaseEast AsianSub910T=1.000C=0.00,
The Genome Aggregation DatabaseEuropeSub17184T=0.936C=0.000
The Genome Aggregation DatabaseGlobalStudy-wide27286T=0.872C=0.000
The Genome Aggregation DatabaseOtherSub260T=0.980C=0.00,
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.856A=0.143
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.960A=0.040
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs81289560.000734alcohol dependence21314694

eQTL of rs8128956 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs8128956 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.