rs8141815

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

MAPK1 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0050 (1521/29964,GnomAD)
A=0059 (1734/29116,TOPMED)
A=0084 (419/5008,1000G)
A=0043 (165/3854,ALSPAC)
A=0045 (166/3708,TWINSUK)

Position: chr22:21837296 (GRCh38.p7) (22q11.22)

Phenotype: AD

Dataset:

GWASdb2

Publications: 2 publication(s)

Genomic View: See rs on genome

Enhancer: 507 Enhancers around

Promoter: 30 Promoters around

Variant Details Frequency Publications p-values eSNP meSNP

Genomic Coordinates

Sequence Name	Change(s)
GRCh38.p7 chr 22	NC_000022.11:g.21837296G>A
GRCh37.p13 chr 22	NC_000022.10:g.22191585G>A
MAPK1 RefSeqGene	LRG_786

Gene: MAPK1, mitogen-activated protein kinase 1(minus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
MAPK1 transcript variant 1	NM_002745.4:c.	N/A	Intron Variant
MAPK1 transcript variant 2	NM_138957.3:c.	N/A	Intron Variant

Population Frequency

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.935	A=0.065
1000Genomes	American	Sub	694	G=0.920	A=0.080
1000Genomes	East Asian	Sub	1008	G=0.889	A=0.111
1000Genomes	Europe	Sub	1006	G=0.955	A=0.045
1000Genomes	Global	Study-wide	5008	G=0.916	A=0.084
1000Genomes	South Asian	Sub	978	G=0.880	A=0.120
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.957	A=0.043
The Genome Aggregation Database	African	Sub	8722	G=0.945	A=0.055
The Genome Aggregation Database	American	Sub	836	G=0.900	A=0.100
The Genome Aggregation Database	East Asian	Sub	1620	G=0.887	A=0.113
The Genome Aggregation Database	Europe	Sub	18484	G=0.958	A=0.041
The Genome Aggregation Database	Global	Study-wide	29964	G=0.949	A=0.050
The Genome Aggregation Database	Other	Sub	302	G=0.960	A=0.040
Trans-Omics for Precision Medicine	Global	Study-wide	29116	G=0.940	A=0.059
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.955	A=0.045

PMID	Title	Author	Journal
24277619	ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.	Quillen EE	Am J Med Genet B Neuropsychiatr Genet
21750581	Genetic association of recovery from eating disorders: the role of GABA receptor SNPs.	Bloss CS	Neuropsychopharmacology

P-Value

SNP ID	p-value	Traits	Study
rs8141815	0.000386	alcohol consumption (maxi-drinks)	24277619

eQTL of rs8141815 in Brain tissues (GTEx Analysis Release V7)

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

meQTL of rs8141815 in Fetal Brain

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr22	22151238	22151565	E067	-40020
chr22	22151694	22151843	E067	-39742
chr22	22152053	22152306	E067	-39279
chr22	22152351	22152502	E067	-39083
chr22	22157298	22157338	E067	-34247
chr22	22157484	22157534	E067	-34051
chr22	22158350	22158563	E067	-33022
chr22	22158743	22158836	E067	-32749
chr22	22161730	22162126	E067	-29459
chr22	22162184	22162234	E067	-29351
chr22	22162286	22162358	E067	-29227
chr22	22162459	22162515	E067	-29070
chr22	22170364	22171810	E067	-19775
chr22	22171826	22171904	E067	-19681
chr22	22172261	22172614	E067	-18971
chr22	22172860	22173437	E067	-18148
chr22	22178312	22178770	E067	-12815
chr22	22186587	22187295	E067	-4290
chr22	22189119	22189575	E067	-2010
chr22	22189709	22189921	E067	-1664
chr22	22190145	22190245	E067	-1340
chr22	22191457	22192230	E067	0
chr22	22192240	22192321	E067	655
chr22	22192343	22192397	E067	758
chr22	22209065	22209105	E067	17480
chr22	22209508	22209587	E067	17923
chr22	22210022	22210146	E067	18437
chr22	22210160	22210311	E067	18575
chr22	22210367	22210440	E067	18782
chr22	22210564	22210862	E067	18979
chr22	22210988	22211166	E067	19403
chr22	22211365	22211409	E067	19780
chr22	22211568	22211608	E067	19983
chr22	22211774	22212174	E067	20189
chr22	22212192	22212354	E067	20607
chr22	22212355	22212428	E067	20770
chr22	22212495	22212637	E067	20910
chr22	22212762	22212929	E067	21177
chr22	22213246	22213438	E067	21661
chr22	22213610	22213660	E067	22025
chr22	22213827	22214023	E067	22242
chr22	22214228	22214525	E067	22643
chr22	22214579	22214638	E067	22994
chr22	22214843	22215030	E067	23258
chr22	22215039	22215175	E067	23454
chr22	22215218	22215271	E067	23633
chr22	22215302	22215379	E067	23717
chr22	22215672	22215744	E067	24087
chr22	22215756	22216188	E067	24171
chr22	22217974	22218035	E067	26389
chr22	22218075	22218197	E067	26490
chr22	22218227	22218313	E067	26642
chr22	22218508	22218580	E067	26923
chr22	22218858	22219042	E067	27273
chr22	22222913	22223036	E067	31328
chr22	22223193	22223298	E067	31608
chr22	22151238	22151565	E068	-40020
chr22	22151694	22151843	E068	-39742
chr22	22152053	22152306	E068	-39279
chr22	22152351	22152502	E068	-39083
chr22	22157298	22157338	E068	-34247
chr22	22157484	22157534	E068	-34051
chr22	22158350	22158563	E068	-33022
chr22	22158743	22158836	E068	-32749
chr22	22160372	22160422	E068	-31163
chr22	22160508	22160555	E068	-31030
chr22	22160579	22160695	E068	-30890
chr22	22161192	22161252	E068	-30333
chr22	22161332	22161388	E068	-30197
chr22	22161549	22161717	E068	-29868
chr22	22161730	22162126	E068	-29459
chr22	22162184	22162234	E068	-29351
chr22	22162286	22162358	E068	-29227
chr22	22162459	22162515	E068	-29070
chr22	22165009	22165107	E068	-26478
chr22	22170364	22171810	E068	-19775
chr22	22171826	22171904	E068	-19681
chr22	22172261	22172614	E068	-18971
chr22	22172860	22173437	E068	-18148
chr22	22173505	22173565	E068	-18020
chr22	22173568	22173672	E068	-17913
chr22	22173676	22173792	E068	-17793
chr22	22173794	22173985	E068	-17600
chr22	22174269	22174319	E068	-17266
chr22	22174435	22174485	E068	-17100
chr22	22174503	22174606	E068	-16979
chr22	22178851	22179072	E068	-12513
chr22	22179082	22179128	E068	-12457
chr22	22179228	22179310	E068	-12275
chr22	22179386	22179457	E068	-12128
chr22	22180044	22180111	E068	-11474
chr22	22180498	22180603	E068	-10982
chr22	22181833	22181873	E068	-9712
chr22	22182065	22182105	E068	-9480
chr22	22182164	22182214	E068	-9371
chr22	22182368	22182471	E068	-9114
chr22	22182613	22182673	E068	-8912
chr22	22182693	22182743	E068	-8842
chr22	22182879	22183150	E068	-8435
chr22	22186587	22187295	E068	-4290
chr22	22188920	22189090	E068	-2495
chr22	22189119	22189575	E068	-2010
chr22	22189709	22189921	E068	-1664
chr22	22190145	22190245	E068	-1340
chr22	22191457	22192230	E068	0
chr22	22192240	22192321	E068	655
chr22	22192343	22192397	E068	758
chr22	22192751	22192866	E068	1166
chr22	22200299	22200351	E068	8714
chr22	22200450	22200842	E068	8865
chr22	22200893	22200943	E068	9308
chr22	22200965	22201055	E068	9380
chr22	22201113	22201318	E068	9528
chr22	22203086	22203181	E068	11501
chr22	22203838	22204108	E068	12253
chr22	22204181	22204231	E068	12596
chr22	22204279	22204549	E068	12694
chr22	22209065	22209105	E068	17480
chr22	22209508	22209587	E068	17923
chr22	22210022	22210146	E068	18437
chr22	22210160	22210311	E068	18575
chr22	22210367	22210440	E068	18782
chr22	22210564	22210862	E068	18979
chr22	22210988	22211166	E068	19403
chr22	22211365	22211409	E068	19780
chr22	22211568	22211608	E068	19983
chr22	22211774	22212174	E068	20189
chr22	22212192	22212354	E068	20607
chr22	22212355	22212428	E068	20770
chr22	22212495	22212637	E068	20910
chr22	22212762	22212929	E068	21177
chr22	22213246	22213438	E068	21661
chr22	22213610	22213660	E068	22025
chr22	22213827	22214023	E068	22242
chr22	22214228	22214525	E068	22643
chr22	22214579	22214638	E068	22994
chr22	22214843	22215030	E068	23258
chr22	22215039	22215175	E068	23454
chr22	22215218	22215271	E068	23633
chr22	22215302	22215379	E068	23717
chr22	22216301	22216404	E068	24716
chr22	22216507	22216567	E068	24922
chr22	22216993	22217139	E068	25408
chr22	22217974	22218035	E068	26389
chr22	22218075	22218197	E068	26490
chr22	22218858	22219042	E068	27273
chr22	22222913	22223036	E068	31328
chr22	22223193	22223298	E068	31608
chr22	22150519	22150563	E069	-41022
chr22	22151238	22151565	E069	-40020
chr22	22151694	22151843	E069	-39742
chr22	22152053	22152306	E069	-39279
chr22	22152351	22152502	E069	-39083
chr22	22157298	22157338	E069	-34247
chr22	22157484	22157534	E069	-34051
chr22	22158350	22158563	E069	-33022
chr22	22158743	22158836	E069	-32749
chr22	22161549	22161717	E069	-29868
chr22	22161730	22162126	E069	-29459
chr22	22162184	22162234	E069	-29351
chr22	22162286	22162358	E069	-29227
chr22	22162459	22162515	E069	-29070
chr22	22170364	22171810	E069	-19775
chr22	22171826	22171904	E069	-19681
chr22	22172261	22172614	E069	-18971
chr22	22172860	22173437	E069	-18148
chr22	22173505	22173565	E069	-18020
chr22	22173568	22173672	E069	-17913
chr22	22173676	22173792	E069	-17793
chr22	22173794	22173985	E069	-17600
chr22	22180044	22180111	E069	-11474
chr22	22182164	22182214	E069	-9371
chr22	22182368	22182471	E069	-9114
chr22	22186587	22187295	E069	-4290
chr22	22189119	22189575	E069	-2010
chr22	22189709	22189921	E069	-1664
chr22	22190145	22190245	E069	-1340
chr22	22191457	22192230	E069	0
chr22	22192240	22192321	E069	655
chr22	22192343	22192397	E069	758
chr22	22192751	22192866	E069	1166
chr22	22192931	22193074	E069	1346
chr22	22193102	22193320	E069	1517
chr22	22193381	22193450	E069	1796
chr22	22203838	22204108	E069	12253
chr22	22204181	22204231	E069	12596
chr22	22208811	22208957	E069	17226
chr22	22209065	22209105	E069	17480
chr22	22209508	22209587	E069	17923
chr22	22210022	22210146	E069	18437
chr22	22210160	22210311	E069	18575
chr22	22210367	22210440	E069	18782
chr22	22210564	22210862	E069	18979
chr22	22211774	22212174	E069	20189
chr22	22212192	22212354	E069	20607
chr22	22212355	22212428	E069	20770
chr22	22212495	22212637	E069	20910
chr22	22212762	22212929	E069	21177
chr22	22213610	22213660	E069	22025
chr22	22213827	22214023	E069	22242
chr22	22214228	22214525	E069	22643
chr22	22214579	22214638	E069	22994
chr22	22214843	22215030	E069	23258
chr22	22215039	22215175	E069	23454
chr22	22215218	22215271	E069	23633
chr22	22215302	22215379	E069	23717
chr22	22215672	22215744	E069	24087
chr22	22215756	22216188	E069	24171
chr22	22216301	22216404	E069	24716
chr22	22216507	22216567	E069	24922
chr22	22216993	22217139	E069	25408
chr22	22217331	22217468	E069	25746
chr22	22217836	22217893	E069	26251
chr22	22217974	22218035	E069	26389
chr22	22218075	22218197	E069	26490
chr22	22218227	22218313	E069	26642
chr22	22218508	22218580	E069	26923
chr22	22218858	22219042	E069	27273
chr22	22208811	22208957	E070	17226
chr22	22209065	22209105	E070	17480
chr22	22218508	22218580	E070	26923
chr22	22218858	22219042	E070	27273
chr22	22151238	22151565	E071	-40020
chr22	22151694	22151843	E071	-39742
chr22	22152053	22152306	E071	-39279
chr22	22152351	22152502	E071	-39083
chr22	22157484	22157534	E071	-34051
chr22	22158350	22158563	E071	-33022
chr22	22158743	22158836	E071	-32749
chr22	22161730	22162126	E071	-29459
chr22	22162184	22162234	E071	-29351
chr22	22162286	22162358	E071	-29227
chr22	22162459	22162515	E071	-29070
chr22	22170364	22171810	E071	-19775
chr22	22171826	22171904	E071	-19681
chr22	22172261	22172614	E071	-18971
chr22	22172860	22173437	E071	-18148
chr22	22173505	22173565	E071	-18020
chr22	22173568	22173672	E071	-17913
chr22	22173676	22173792	E071	-17793
chr22	22173794	22173985	E071	-17600
chr22	22174269	22174319	E071	-17266
chr22	22174435	22174485	E071	-17100
chr22	22174503	22174606	E071	-16979
chr22	22181372	22181422	E071	-10163
chr22	22181604	22181654	E071	-9931
chr22	22181747	22181798	E071	-9787
chr22	22181833	22181873	E071	-9712
chr22	22182065	22182105	E071	-9480
chr22	22182164	22182214	E071	-9371
chr22	22182368	22182471	E071	-9114
chr22	22182613	22182673	E071	-8912
chr22	22182693	22182743	E071	-8842
chr22	22186040	22186090	E071	-5495
chr22	22186212	22186311	E071	-5274
chr22	22186408	22186462	E071	-5123
chr22	22186522	22186583	E071	-5002
chr22	22186587	22187295	E071	-4290
chr22	22188920	22189090	E071	-2495
chr22	22189119	22189575	E071	-2010
chr22	22189709	22189921	E071	-1664
chr22	22190145	22190245	E071	-1340
chr22	22191457	22192230	E071	0
chr22	22192240	22192321	E071	655
chr22	22192343	22192397	E071	758
chr22	22198811	22199106	E071	7226
chr22	22200450	22200842	E071	8865
chr22	22200893	22200943	E071	9308
chr22	22200965	22201055	E071	9380
chr22	22208811	22208957	E071	17226
chr22	22209065	22209105	E071	17480
chr22	22209508	22209587	E071	17923
chr22	22210022	22210146	E071	18437
chr22	22210160	22210311	E071	18575
chr22	22210367	22210440	E071	18782
chr22	22210564	22210862	E071	18979
chr22	22210988	22211166	E071	19403
chr22	22211365	22211409	E071	19780
chr22	22211568	22211608	E071	19983
chr22	22211774	22212174	E071	20189
chr22	22212192	22212354	E071	20607
chr22	22212355	22212428	E071	20770
chr22	22212495	22212637	E071	20910
chr22	22212762	22212929	E071	21177
chr22	22214228	22214525	E071	22643
chr22	22214579	22214638	E071	22994
chr22	22214843	22215030	E071	23258
chr22	22215039	22215175	E071	23454
chr22	22215218	22215271	E071	23633
chr22	22215302	22215379	E071	23717
chr22	22215672	22215744	E071	24087
chr22	22215756	22216188	E071	24171
chr22	22216301	22216404	E071	24716
chr22	22216507	22216567	E071	24922
chr22	22218227	22218313	E071	26642
chr22	22218508	22218580	E071	26923
chr22	22218858	22219042	E071	27273
chr22	22151238	22151565	E072	-40020
chr22	22151694	22151843	E072	-39742
chr22	22152053	22152306	E072	-39279
chr22	22158350	22158563	E072	-33022
chr22	22158743	22158836	E072	-32749
chr22	22161730	22162126	E072	-29459
chr22	22162184	22162234	E072	-29351
chr22	22162286	22162358	E072	-29227
chr22	22162459	22162515	E072	-29070
chr22	22171826	22171904	E072	-19681
chr22	22172261	22172614	E072	-18971
chr22	22172860	22173437	E072	-18148
chr22	22173505	22173565	E072	-18020
chr22	22173568	22173672	E072	-17913
chr22	22173676	22173792	E072	-17793
chr22	22173794	22173985	E072	-17600
chr22	22182065	22182105	E072	-9480
chr22	22182164	22182214	E072	-9371
chr22	22182368	22182471	E072	-9114
chr22	22186408	22186462	E072	-5123
chr22	22186522	22186583	E072	-5002
chr22	22186587	22187295	E072	-4290
chr22	22188920	22189090	E072	-2495
chr22	22189119	22189575	E072	-2010
chr22	22189709	22189921	E072	-1664
chr22	22190145	22190245	E072	-1340
chr22	22191457	22192230	E072	0
chr22	22192240	22192321	E072	655
chr22	22192343	22192397	E072	758
chr22	22192751	22192866	E072	1166
chr22	22192931	22193074	E072	1346
chr22	22193102	22193320	E072	1517
chr22	22203838	22204108	E072	12253
chr22	22204181	22204231	E072	12596
chr22	22208811	22208957	E072	17226
chr22	22209065	22209105	E072	17480
chr22	22209508	22209587	E072	17923
chr22	22210022	22210146	E072	18437
chr22	22210160	22210311	E072	18575
chr22	22210367	22210440	E072	18782
chr22	22210564	22210862	E072	18979
chr22	22210988	22211166	E072	19403
chr22	22211365	22211409	E072	19780
chr22	22211568	22211608	E072	19983
chr22	22211774	22212174	E072	20189
chr22	22212192	22212354	E072	20607
chr22	22212355	22212428	E072	20770
chr22	22212495	22212637	E072	20910
chr22	22212762	22212929	E072	21177
chr22	22214228	22214525	E072	22643
chr22	22214579	22214638	E072	22994
chr22	22214843	22215030	E072	23258
chr22	22215039	22215175	E072	23454
chr22	22215218	22215271	E072	23633
chr22	22215302	22215379	E072	23717
chr22	22215672	22215744	E072	24087
chr22	22215756	22216188	E072	24171
chr22	22222913	22223036	E072	31328
chr22	22223193	22223298	E072	31608
chr22	22151238	22151565	E073	-40020
chr22	22151694	22151843	E073	-39742
chr22	22152053	22152306	E073	-39279
chr22	22152351	22152502	E073	-39083
chr22	22158350	22158563	E073	-33022
chr22	22158743	22158836	E073	-32749
chr22	22162184	22162234	E073	-29351
chr22	22162286	22162358	E073	-29227
chr22	22170364	22171810	E073	-19775
chr22	22171826	22171904	E073	-19681
chr22	22172261	22172614	E073	-18971
chr22	22172860	22173437	E073	-18148
chr22	22173505	22173565	E073	-18020
chr22	22173568	22173672	E073	-17913
chr22	22173676	22173792	E073	-17793
chr22	22173794	22173985	E073	-17600
chr22	22182065	22182105	E073	-9480
chr22	22182164	22182214	E073	-9371
chr22	22182368	22182471	E073	-9114
chr22	22182613	22182673	E073	-8912
chr22	22182693	22182743	E073	-8842
chr22	22182879	22183150	E073	-8435
chr22	22188920	22189090	E073	-2495
chr22	22189119	22189575	E073	-2010
chr22	22189709	22189921	E073	-1664
chr22	22190145	22190245	E073	-1340
chr22	22191457	22192230	E073	0
chr22	22209065	22209105	E073	17480
chr22	22209508	22209587	E073	17923
chr22	22210022	22210146	E073	18437
chr22	22210160	22210311	E073	18575
chr22	22210367	22210440	E073	18782
chr22	22210564	22210862	E073	18979
chr22	22210988	22211166	E073	19403
chr22	22211365	22211409	E073	19780
chr22	22211568	22211608	E073	19983
chr22	22211774	22212174	E073	20189
chr22	22212192	22212354	E073	20607
chr22	22212355	22212428	E073	20770
chr22	22212495	22212637	E073	20910
chr22	22212762	22212929	E073	21177
chr22	22214579	22214638	E073	22994
chr22	22215039	22215175	E073	23454
chr22	22215218	22215271	E073	23633
chr22	22215302	22215379	E073	23717
chr22	22215672	22215744	E073	24087
chr22	22215756	22216188	E073	24171
chr22	22150519	22150563	E074	-41022
chr22	22151238	22151565	E074	-40020
chr22	22151694	22151843	E074	-39742
chr22	22152053	22152306	E074	-39279
chr22	22152351	22152502	E074	-39083
chr22	22157484	22157534	E074	-34051
chr22	22158350	22158563	E074	-33022
chr22	22158743	22158836	E074	-32749
chr22	22161549	22161717	E074	-29868
chr22	22161730	22162126	E074	-29459
chr22	22162184	22162234	E074	-29351
chr22	22170364	22171810	E074	-19775
chr22	22172860	22173437	E074	-18148
chr22	22173505	22173565	E074	-18020
chr22	22173568	22173672	E074	-17913
chr22	22173676	22173792	E074	-17793
chr22	22173794	22173985	E074	-17600
chr22	22181152	22181267	E074	-10318
chr22	22181372	22181422	E074	-10163
chr22	22181604	22181654	E074	-9931
chr22	22181747	22181798	E074	-9787
chr22	22181833	22181873	E074	-9712
chr22	22182065	22182105	E074	-9480
chr22	22182164	22182214	E074	-9371
chr22	22182368	22182471	E074	-9114
chr22	22186040	22186090	E074	-5495
chr22	22186212	22186311	E074	-5274
chr22	22186408	22186462	E074	-5123
chr22	22186522	22186583	E074	-5002
chr22	22186587	22187295	E074	-4290
chr22	22187357	22187499	E074	-4086
chr22	22187517	22187588	E074	-3997
chr22	22188920	22189090	E074	-2495
chr22	22189119	22189575	E074	-2010
chr22	22189709	22189921	E074	-1664
chr22	22190145	22190245	E074	-1340
chr22	22191457	22192230	E074	0
chr22	22198811	22199106	E074	7226
chr22	22200450	22200842	E074	8865
chr22	22200893	22200943	E074	9308
chr22	22200965	22201055	E074	9380
chr22	22201113	22201318	E074	9528
chr22	22203086	22203181	E074	11501
chr22	22208811	22208957	E074	17226
chr22	22209065	22209105	E074	17480
chr22	22209508	22209587	E074	17923
chr22	22210022	22210146	E074	18437
chr22	22210160	22210311	E074	18575
chr22	22210367	22210440	E074	18782
chr22	22210564	22210862	E074	18979
chr22	22210988	22211166	E074	19403
chr22	22211365	22211409	E074	19780
chr22	22211568	22211608	E074	19983
chr22	22211774	22212174	E074	20189
chr22	22212192	22212354	E074	20607
chr22	22212355	22212428	E074	20770
chr22	22212495	22212637	E074	20910
chr22	22212762	22212929	E074	21177
chr22	22213246	22213438	E074	21661
chr22	22214228	22214525	E074	22643
chr22	22214579	22214638	E074	22994
chr22	22214843	22215030	E074	23258
chr22	22215039	22215175	E074	23454
chr22	22215218	22215271	E074	23633
chr22	22215302	22215379	E074	23717
chr22	22218858	22219042	E074	27273
chr22	22186408	22186462	E081	-5123
chr22	22186522	22186583	E081	-5002
chr22	22186587	22187295	E081	-4290
chr22	22191457	22192230	E081	0
chr22	22192240	22192321	E081	655
chr22	22192343	22192397	E081	758
chr22	22200450	22200842	E081	8865
chr22	22200893	22200943	E081	9308
chr22	22200965	22201055	E081	9380
chr22	22201113	22201318	E081	9528
chr22	22210022	22210146	E081	18437
chr22	22210160	22210311	E081	18575
chr22	22210367	22210440	E081	18782
chr22	22218508	22218580	E081	26923
chr22	22218858	22219042	E081	27273
chr22	22222913	22223036	E081	31328
chr22	22173505	22173565	E082	-18020
chr22	22173568	22173672	E082	-17913
chr22	22173676	22173792	E082	-17793
chr22	22173794	22173985	E082	-17600
chr22	22186587	22187295	E082	-4290
chr22	22191457	22192230	E082	0
chr22	22200450	22200842	E082	8865
chr22	22200893	22200943	E082	9308
chr22	22200965	22201055	E082	9380
chr22	22210022	22210146	E082	18437
chr22	22210160	22210311	E082	18575
chr22	22210367	22210440	E082	18782
chr22	22214228	22214525	E082	22643
chr22	22214579	22214638	E082	22994
chr22	22215756	22216188	E082	24171
chr22	22217974	22218035	E082	26389
chr22	22218075	22218197	E082	26490
chr22	22218227	22218313	E082	26642
chr22	22218508	22218580	E082	26923
chr22	22218858	22219042	E082	27273
chr22	22222913	22223036	E082	31328
chr22	22223193	22223298	E082	31608

Promoter Annotation (GRCh37.p13)

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr22	22220062	22220216	E067	28477
chr22	22220288	22220457	E067	28703
chr22	22220547	22222692	E067	28962
chr22	22220062	22220216	E068	28477
chr22	22220288	22220457	E068	28703
chr22	22220547	22222692	E068	28962
chr22	22220062	22220216	E069	28477
chr22	22220288	22220457	E069	28703
chr22	22220547	22222692	E069	28962
chr22	22220062	22220216	E070	28477
chr22	22220288	22220457	E070	28703
chr22	22220547	22222692	E070	28962
chr22	22220062	22220216	E071	28477
chr22	22220288	22220457	E071	28703
chr22	22220547	22222692	E071	28962
chr22	22220062	22220216	E072	28477
chr22	22220288	22220457	E072	28703
chr22	22220547	22222692	E072	28962
chr22	22220062	22220216	E073	28477
chr22	22220288	22220457	E073	28703
chr22	22220547	22222692	E073	28962
chr22	22220062	22220216	E074	28477
chr22	22220288	22220457	E074	28703
chr22	22220547	22222692	E074	28962
chr22	22220062	22220216	E081	28477
chr22	22220288	22220457	E081	28703
chr22	22220547	22222692	E081	28962
chr22	22220062	22220216	E082	28477
chr22	22220288	22220457	E082	28703
chr22	22220547	22222692	E082	28962