rs8185226

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0497 (14772/29716,GnomAD)
T==0484 (2424/5008,1000G)
C=0469 (1807/3854,ALSPAC)
C=0466 (1728/3708,TWINSUK)
chr5:46160685 (GRCh38.p7) (5p11)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.46160685T>C
GRCh37.p13 chr 5NC_000005.9:g.46160787T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.317C=0.683
1000GenomesAmericanSub694T=0.590C=0.410
1000GenomesEast AsianSub1008T=0.523C=0.477
1000GenomesEuropeSub1006T=0.554C=0.446
1000GenomesGlobalStudy-wide5008T=0.484C=0.516
1000GenomesSouth AsianSub978T=0.520C=0.480
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.531C=0.469
The Genome Aggregation DatabaseAfricanSub8694T=0.323C=0.677
The Genome Aggregation DatabaseAmericanSub826T=0.620C=0.380
The Genome Aggregation DatabaseEast AsianSub1512T=0.483C=0.517
The Genome Aggregation DatabaseEuropeSub18382T=0.585C=0.414
The Genome Aggregation DatabaseGlobalStudy-wide29716T=0.502C=0.497
The Genome Aggregation DatabaseOtherSub302T=0.460C=0.540
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.534C=0.466
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs81852260.000811alcohol dependence20201924

eQTL of rs8185226 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs8185226 in Fetal Brain

Probe ID Position Gene beta p-value
cg15950743chr5:49708521EMB0.06374333192472615.3711e-16

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.