rs827628

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0244 (7132/29118,TOPMED)
T==0247 (6852/27672,GnomAD)
T==0194 (972/5008,1000G)
T==0281 (1084/3854,ALSPAC)
T==0287 (1065/3708,TWINSUK)
chr10:8978271 (GRCh38.p7) (10p14)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.8978271T>C
GRCh37.p13 chr 10NC_000010.10:g.9020234T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.196C=0.804
1000GenomesAmericanSub694T=0.310C=0.690
1000GenomesEast AsianSub1008T=0.145C=0.855
1000GenomesEuropeSub1006T=0.280C=0.720
1000GenomesGlobalStudy-wide5008T=0.194C=0.806
1000GenomesSouth AsianSub978T=0.070C=0.930
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.281C=0.719
The Genome Aggregation DatabaseAfricanSub8188T=0.216C=0.784
The Genome Aggregation DatabaseAmericanSub736T=0.290C=0.710
The Genome Aggregation DatabaseEast AsianSub1578T=0.149C=0.851
The Genome Aggregation DatabaseEuropeSub16876T=0.270C=0.729
The Genome Aggregation DatabaseGlobalStudy-wide27672T=0.247C=0.752
The Genome Aggregation DatabaseOtherSub294T=0.240C=0.760
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.244C=0.755
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.287C=0.713
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs8276280.000319alcohol dependence20201924

eQTL of rs827628 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs827628 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.