rs835315

Homo sapiens
G>A
UGT2B10 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G==0216 (6457/29850,GnomAD)
G==0288 (8391/29118,TOPMED)
G==0233 (1167/5008,1000G)
G==0099 (383/3854,ALSPAC)
G==0115 (425/3708,TWINSUK)
chr4:68820054 (GRCh38.p7) (4q13.2)
ND
GWASCatalog
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.68820054G>A
GRCh37.p13 chr 4NC_000004.11:g.69685772G>A
GRCh38.p7 chr 4 alt locus HSCHR4_1_CTG9NT_167250.2:g.396073G>A
GRCh37.p13 chr 4 alt locus HSCHR4_1_CTG9NT_167250.1:g.398023G>A

Gene: UGT2B10, UDP glucuronosyltransferase family 2 member B10(plus strand)

Molecule type Change Amino acid[Codon] SO Term
UGT2B10 transcript variant 1NM_001075.5:c.N/AIntron Variant
UGT2B10 transcript variant 2NM_001144767.2:c.N/AIntron Variant
UGT2B10 transcript variant 3NM_001290091.1:c.N/AIntron Variant
UGT2B10 transcript variant X1XM_017008585.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.617A=0.383
1000GenomesAmericanSub694G=0.160A=0.840
1000GenomesEast AsianSub1008G=0.086A=0.914
1000GenomesEuropeSub1006G=0.093A=0.907
1000GenomesGlobalStudy-wide5008G=0.233A=0.767
1000GenomesSouth AsianSub978G=0.060A=0.940
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.099A=0.901
The Genome Aggregation DatabaseAfricanSub8668G=0.534A=0.466
The Genome Aggregation DatabaseAmericanSub838G=0.120A=0.880
The Genome Aggregation DatabaseEast AsianSub1584G=0.090A=0.910
The Genome Aggregation DatabaseEuropeSub18458G=0.084A=0.915
The Genome Aggregation DatabaseGlobalStudy-wide29850G=0.216A=0.783
The Genome Aggregation DatabaseOtherSub302G=0.120A=0.880
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.288A=0.711
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.115A=0.885
PMID Title Author Journal
25293881The contribution of common genetic variation to nicotine and cotinine glucuronidation in multiple ethnic/racial populations.Patel YMCancer Epidemiol Biomarkers Prev

P-Value

SNP ID p-value Traits Study
rs8353153E-43nicotine glucouronidation25293881

eQTL of rs835315 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs835315 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.