SNP Detail Info-rs851860

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A==0145 (4345/29962,GnomAD)
A==0124 (3626/29118,TOPMED)
A==0109 (548/5008,1000G)
A==0188 (726/3854,ALSPAC)
A==0174 (645/3708,TWINSUK)

Position: chr6:66344991 (GRCh38.p7) (6q12)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 1 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 6	NC_000006.12:g.66344991A>G
GRCh37.p13 chr 6	NC_000006.11:g.67054884A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.048	G=0.952
1000Genomes	American	Sub	694	A=0.210	G=0.790
1000Genomes	East Asian	Sub	1008	A=0.054	G=0.946
1000Genomes	Europe	Sub	1006	A=0.182	G=0.818
1000Genomes	Global	Study-wide	5008	A=0.109	G=0.891
1000Genomes	South Asian	Sub	978	A=0.110	G=0.890
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.188	G=0.812
The Genome Aggregation Database	African	Sub	8732	A=0.066	G=0.934
The Genome Aggregation Database	American	Sub	836	A=0.170	G=0.830
The Genome Aggregation Database	East Asian	Sub	1620	A=0.049	G=0.951
The Genome Aggregation Database	Europe	Sub	18472	A=0.188	G=0.811
The Genome Aggregation Database	Global	Study-wide	29962	A=0.145	G=0.855
The Genome Aggregation Database	Other	Sub	302	A=0.210	G=0.790
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.124	G=0.875
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.174	G=0.826

PMID	Title	Author	Journal
24277619	ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.	Quillen EE	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs851860	0.000494	alcohol dependence	24277619

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs851860