rs855250

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0171 (5146/29966,GnomAD)
C=0204 (5957/29118,TOPMED)
C=0156 (782/5008,1000G)
C=0161 (619/3854,ALSPAC)
C=0146 (540/3708,TWINSUK)
chr6:9608654 (GRCh38.p7) (6p24.3)
AD
GWASdb2
1   publication(s)
See rs on genome
6 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.9608654A>C
GRCh37.p13 chr 6NC_000006.11:g.9608887A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.719C=0.281
1000GenomesAmericanSub694A=0.870C=0.130
1000GenomesEast AsianSub1008A=0.971C=0.029
1000GenomesEuropeSub1006A=0.838C=0.162
1000GenomesGlobalStudy-wide5008A=0.844C=0.156
1000GenomesSouth AsianSub978A=0.870C=0.130
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.839C=0.161
The Genome Aggregation DatabaseAfricanSub8710A=0.730C=0.270
The Genome Aggregation DatabaseAmericanSub838A=0.890C=0.110
The Genome Aggregation DatabaseEast AsianSub1622A=0.980C=0.020
The Genome Aggregation DatabaseEuropeSub18494A=0.859C=0.140
The Genome Aggregation DatabaseGlobalStudy-wide29966A=0.828C=0.171
The Genome Aggregation DatabaseOtherSub302A=0.760C=0.240
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.795C=0.204
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.854C=0.146
PMID Title Author Journal
21703634A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.Wang KSJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs8552509.94E-05alcohol dependence21703634

eQTL of rs855250 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs855250 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr695643029564550E070-44337
chr695646389564700E070-44187
chr695647639564843E070-44044
chr696106999610796E0811812
chr696108409610920E0811953
chr696111889611345E0812301