rs858723

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0219 (6575/29920,GnomAD)
C==0220 (6431/29118,TOPMED)
C==0254 (1271/5008,1000G)
C==0199 (767/3854,ALSPAC)
C==0208 (773/3708,TWINSUK)
chr11:130224731 (GRCh38.p7) (11q24.3)
ND
GWASdb2
1   publication(s)
See rs on genome
92 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.130224731C>T
GRCh37.p13 chr 11NC_000011.9:g.130094626C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.272T=0.728
1000GenomesAmericanSub694C=0.140T=0.860
1000GenomesEast AsianSub1008C=0.452T=0.548
1000GenomesEuropeSub1006C=0.169T=0.831
1000GenomesGlobalStudy-wide5008C=0.254T=0.746
1000GenomesSouth AsianSub978C=0.200T=0.800
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.199T=0.801
The Genome Aggregation DatabaseAfricanSub8702C=0.269T=0.731
The Genome Aggregation DatabaseAmericanSub838C=0.140T=0.860
The Genome Aggregation DatabaseEast AsianSub1618C=0.470T=0.530
The Genome Aggregation DatabaseEuropeSub18460C=0.179T=0.820
The Genome Aggregation DatabaseGlobalStudy-wide29920C=0.219T=0.780
The Genome Aggregation DatabaseOtherSub302C=0.160T=0.840
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.220T=0.779
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.208T=0.792
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs8587230.000426nicotine smoking19268276

eQTL of rs858723 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs858723 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr11130116649130116995E06722023
chr11130117228130117278E06722602
chr11130117531130117597E06722905
chr11130119609130119708E06724983
chr11130130642130130962E06736016
chr11130131252130131811E06736626
chr11130135927130136322E06741301
chr11130136362130136412E06741736
chr11130136608130136668E06741982
chr11130050902130050962E068-43664
chr11130050991130051041E068-43585
chr11130051106130052363E068-42263
chr11130116299130116506E06821673
chr11130116649130116995E06822023
chr11130117228130117278E06822602
chr11130117531130117597E06822905
chr11130135927130136322E06841301
chr11130136362130136412E06841736
chr11130140068130140165E06845442
chr11130116649130116995E06922023
chr11130117228130117278E06922602
chr11130117531130117597E06922905
chr11130133025130133075E06938399
chr11130133283130133619E06938657
chr11130135927130136322E06941301
chr11130136362130136412E06941736
chr11130082692130083894E070-10732
chr11130082692130083894E071-10732
chr11130109240130109435E07114614
chr11130113190130113385E07118564
chr11130113807130113994E07119181
chr11130116299130116506E07121673
chr11130116649130116995E07122023
chr11130117228130117278E07122602
chr11130117531130117597E07122905
chr11130119609130119708E07124983
chr11130126077130126131E07131451
chr11130130642130130962E07136016
chr11130131252130131811E07136626
chr11130135927130136322E07141301
chr11130136362130136412E07141736
chr11130116299130116506E07221673
chr11130116649130116995E07222023
chr11130117228130117278E07222602
chr11130117531130117597E07222905
chr11130133283130133619E07238657
chr11130133682130133799E07239056
chr11130135927130136322E07241301
chr11130142853130142935E07248227
chr11130089944130090006E073-4620
chr11130090119130090163E073-4463
chr11130117228130117278E07322602
chr11130050902130050962E074-43664
chr11130050991130051041E074-43585
chr11130109240130109435E07414614
chr11130115430130115537E07420804
chr11130115629130116021E07421003
chr11130116299130116506E07421673
chr11130116649130116995E07422023
chr11130117228130117278E07422602
chr11130117531130117597E07422905
chr11130135927130136322E07441301
chr11130136362130136412E07441736
chr11130142853130142935E07448227
chr11130052426130052511E081-42115
chr11130053139130053313E081-41313
chr11130053603130053721E081-40905
chr11130053790130054131E081-40495
chr11130054177130054558E081-40068
chr11130078549130078620E081-16006
chr11130082692130083894E081-10732
chr11130084079130084139E081-10487
chr11130084175130084229E081-10397
chr11130115629130116021E08121003
chr11130116299130116506E08121673
chr11130117228130117278E08122602
chr11130117531130117597E08122905
chr11130130642130130962E08136016
chr11130131252130131811E08136626
chr11130131902130132035E08137276
chr11130132933130132983E08138307
chr11130133025130133075E08138399
chr11130133283130133619E08138657
chr11130053603130053721E082-40905
chr11130053790130054131E082-40495
chr11130131252130131811E08236626
chr11130132933130132983E08238307
chr11130133025130133075E08238399
chr11130133283130133619E08238657
chr11130133682130133799E08239056
chr11130133851130133946E08239225
chr11130133987130134051E08239361