rs868827

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
G==0166 (5000/29960,GnomAD)
G==0194 (5663/29118,TOPMED)
G==0190 (950/5008,1000G)
G==0120 (462/3854,ALSPAC)
G==0104 (386/3708,TWINSUK)
chr14:61235011 (GRCh38.p7) (14q23.1)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
17 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.61235011G>A
GRCh37.p13 chr 14NC_000014.8:g.61701729G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.313A=0.687
1000GenomesAmericanSub694G=0.120A=0.880
1000GenomesEast AsianSub1008G=0.191A=0.809
1000GenomesEuropeSub1006G=0.125A=0.875
1000GenomesGlobalStudy-wide5008G=0.190A=0.810
1000GenomesSouth AsianSub978G=0.140A=0.860
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.120A=0.880
The Genome Aggregation DatabaseAfricanSub8714G=0.308A=0.692
The Genome Aggregation DatabaseAmericanSub838G=0.080A=0.920
The Genome Aggregation DatabaseEast AsianSub1622G=0.197A=0.803
The Genome Aggregation DatabaseEuropeSub18484G=0.102A=0.897
The Genome Aggregation DatabaseGlobalStudy-wide29960G=0.166A=0.833
The Genome Aggregation DatabaseOtherSub302G=0.130A=0.870
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.194A=0.805
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.104A=0.896
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs8688270.000959alcohol dependence20201924

eQTL of rs868827 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs868827 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr146171897961719815E07117250
chr146172009961720434E07118370

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr146165560961656364E067-45365
chr146173618061736923E06734451
chr146174570161749025E06743972
chr146165487461655312E068-46417
chr146165531761655379E068-46350
chr146165560961656364E068-45365
chr146174570161749025E06843972
chr146165560961656364E069-45365
chr146174570161749025E06943972
chr146165531761655379E070-46350
chr146165531761655379E071-46350
chr146165560961656364E071-45365
chr146174570161749025E07143972
chr146165560961656364E072-45365
chr146165560961656364E073-45365
chr146174570161749025E07343972
chr146173618061736923E08134451