rs872526

Homo sapiens
A>C
GRIP2 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0361 (10779/29820,GnomAD)
C=0342 (9979/29118,TOPMED)
C=0448 (2244/5008,1000G)
C=0415 (1601/3854,ALSPAC)
C=0441 (1634/3708,TWINSUK)
chr3:14519332 (GRCh38.p7) (3p25.1)
ND
GWASdb2
1   publication(s)
See rs on genome
75 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.14519332A>C
GRCh37.p13 chr 3NC_000003.11:g.14560840A>C

Gene: GRIP2, glutamate receptor interacting protein 2(minus strand)

Molecule type Change Amino acid[Codon] SO Term
GRIP2 transcriptNM_001080423.3:c.N/AIntron Variant
GRIP2 transcript variant X1XM_011534141.2:c.N/AIntron Variant
GRIP2 transcript variant X2XM_011534142.2:c.N/AIntron Variant
GRIP2 transcript variant X3XM_011534143.2:c.N/AIntron Variant
GRIP2 transcript variant X5XM_011534145.2:c.N/AIntron Variant
GRIP2 transcript variant X6XM_011534146.2:c.N/AIntron Variant
GRIP2 transcript variant X4XR_940504.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.780C=0.220
1000GenomesAmericanSub694A=0.470C=0.530
1000GenomesEast AsianSub1008A=0.432C=0.568
1000GenomesEuropeSub1006A=0.599C=0.401
1000GenomesGlobalStudy-wide5008A=0.552C=0.448
1000GenomesSouth AsianSub978A=0.380C=0.620
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.585C=0.415
The Genome Aggregation DatabaseAfricanSub8680A=0.758C=0.242
The Genome Aggregation DatabaseAmericanSub838A=0.480C=0.520
The Genome Aggregation DatabaseEast AsianSub1614A=0.457C=0.543
The Genome Aggregation DatabaseEuropeSub18388A=0.604C=0.395
The Genome Aggregation DatabaseGlobalStudy-wide29820A=0.638C=0.361
The Genome Aggregation DatabaseOtherSub300A=0.680C=0.320
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.657C=0.342
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.559C=0.441
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs8725260.000308nicotine smoking19268276

eQTL of rs872526 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs872526 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr31457606514576234E06715225
chr31457629814576573E06715458
chr31452343914523499E068-37341
chr31452353814523603E068-37237
chr31452365114523828E068-37012
chr31455036014550939E069-9901
chr31455096014551052E069-9788
chr31457673514576787E06915895
chr31455096014551052E070-9788
chr31455284614552896E070-7944
chr31455325514553436E070-7404
chr31455355814553608E070-7232
chr31457399314574129E07013153
chr31457420614574493E07013366
chr31457452614574969E07013686
chr31457497114575034E07014131
chr31457503614575143E07014196
chr31457533114575392E07014491
chr31457550114575563E07014661
chr31457893614578990E07018096
chr31457928014579461E07018440
chr31457951014579651E07018670
chr31458492414585238E07024084
chr31458534414585384E07024504
chr31458969614590137E07028856
chr31460500914605059E07044169
chr31460514314605249E07044303
chr31460550814605818E07044668
chr31457606514576234E07115225
chr31457629814576573E07115458
chr31457673514576787E07115895
chr31452947814529525E073-31315
chr31455036014550939E073-9901
chr31455096014551052E073-9788
chr31452830314528427E081-32413
chr31452877914528823E081-32017
chr31452891714529037E081-31803
chr31452903914529100E081-31740
chr31452914714529227E081-31613
chr31452933614529380E081-31460
chr31452947814529525E081-31315
chr31452969314529751E081-31089
chr31452979814529886E081-30954
chr31453000414530121E081-30719
chr31453019014530691E081-30149
chr31453100514531143E081-29697
chr31453137114531441E081-29399
chr31457420614574493E08113366
chr31457452614574969E08113686
chr31457497114575034E08114131
chr31457503614575143E08114196
chr31457533114575392E08114491
chr31457550114575563E08114661
chr31457606514576234E08115225
chr31457629814576573E08115458
chr31457673514576787E08115895
chr31458492414585238E08124084
chr31458534414585384E08124504
chr31459777814597903E08136938
chr31460403514604399E08143195
chr31460462614604686E08143786
chr31460500914605059E08144169
chr31460514314605249E08144303
chr31460550814605818E08144668
chr31460635914606478E08145519
chr31458492414585238E08224084
chr31458534414585384E08224504
chr31459777814597903E08236938
chr31459805014598121E08237210
chr31460363114603974E08242791
chr31460403514604399E08243195
chr31460462614604686E08243786
chr31460500914605059E08244169
chr31460514314605249E08244303
chr31460550814605818E08244668








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr31458134414581485E06720504
chr31458163214581692E06720792
chr31458134414581485E07020504
chr31458163214581692E07020792
chr31458184114581967E07021001
chr31458163214581692E07120792
chr31458184114581967E07121001
chr31458134414581485E08220504
chr31458163214581692E08220792
chr31458184114581967E08221001