rs877800

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0221 (6634/29902,GnomAD)
C==0215 (6274/29118,TOPMED)
C==0155 (778/5008,1000G)
C==0299 (1152/3854,ALSPAC)
C==0324 (1203/3708,TWINSUK)
chr14:83725901 (GRCh38.p7) (14q31.2)
AD
GWASdb2
1   publication(s)
See rs on genome
10 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.83725901C>T
GRCh37.p13 chr 14NC_000014.8:g.84192245C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.118T=0.882
1000GenomesAmericanSub694C=0.200T=0.800
1000GenomesEast AsianSub1008C=0.033T=0.967
1000GenomesEuropeSub1006C=0.300T=0.700
1000GenomesGlobalStudy-wide5008C=0.155T=0.845
1000GenomesSouth AsianSub978C=0.150T=0.850
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.299T=0.701
The Genome Aggregation DatabaseAfricanSub8702C=0.146T=0.854
The Genome Aggregation DatabaseAmericanSub836C=0.170T=0.830
The Genome Aggregation DatabaseEast AsianSub1596C=0.034T=0.966
The Genome Aggregation DatabaseEuropeSub18466C=0.277T=0.723
The Genome Aggregation DatabaseGlobalStudy-wide29902C=0.221T=0.778
The Genome Aggregation DatabaseOtherSub302C=0.200T=0.800
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.215T=0.784
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.324T=0.676
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs8778000.000819alcohol dependence20201924

eQTL of rs877800 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs877800 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr148417259184173554E081-18691
chr148417639784176487E081-15758
chr148417716984177239E081-15006
chr148417739384178470E081-13775
chr148418076884180904E081-11341
chr148421263984213018E08120394
chr148421321084213277E08120965
chr148421338684213449E08121141
chr148421356184213747E08121316
chr148417739384178470E082-13775