rs879533

Homo sapiens
T>A
None
Check p-value
SNV (Single Nucleotide Variation)
T==0474 (14185/29912,GnomAD)
T==0441 (12847/29118,TOPMED)
A=0484 (2422/5008,1000G)
T==0477 (1839/3854,ALSPAC)
T==0493 (1829/3708,TWINSUK)
chr2:129239173 (GRCh38.p7) (2q21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
16 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.129239173T>A
GRCh37.p13 chr 2NC_000002.11:g.129996746T>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.340A=0.660
1000GenomesAmericanSub694T=0.530A=0.470
1000GenomesEast AsianSub1008T=0.749A=0.251
1000GenomesEuropeSub1006T=0.464A=0.536
1000GenomesGlobalStudy-wide5008T=0.516A=0.484
1000GenomesSouth AsianSub978T=0.560A=0.440
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.477A=0.523
The Genome Aggregation DatabaseAfricanSub8706T=0.388A=0.612
The Genome Aggregation DatabaseAmericanSub834T=0.550A=0.450
The Genome Aggregation DatabaseEast AsianSub1618T=0.804A=0.196
The Genome Aggregation DatabaseEuropeSub18452T=0.483A=0.516
The Genome Aggregation DatabaseGlobalStudy-wide29912T=0.474A=0.525
The Genome Aggregation DatabaseOtherSub302T=0.440A=0.560
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.441A=0.558
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.493A=0.507
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs8795337.46E-07alcohol dependence (age at onset)24962325

eQTL of rs879533 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs879533 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2129990903129991022E070-5724
chr2129991443129991904E070-4842
chr2129990903129991022E081-5724
chr2129991443129991904E081-4842
chr2129996773129997036E08127
chr2130010223130010353E08113477
chr2130010398130011293E08113652
chr2130038915130039052E08142169
chr2130039472130039687E08142726
chr2130039843130039996E08143097
chr2129996773129997036E08227
chr2130010223130010353E08213477
chr2130038591130038845E08241845
chr2130038915130039052E08242169
chr2130039472130039687E08242726
chr2130039843130039996E08243097