rs885685

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0451 (13507/29912,GnomAD)
A=0449 (13090/29118,TOPMED)
A=0439 (2199/5008,1000G)
A=0457 (1763/3854,ALSPAC)
A=0440 (1631/3708,TWINSUK)
chr7:48888701 (GRCh38.p7) (7p12.3)
AD
GWASdb2
1   publication(s)
See rs on genome
24 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.48888701G>A
GRCh37.p13 chr 7NC_000007.13:g.48928297G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.507A=0.493
1000GenomesAmericanSub694G=0.560A=0.440
1000GenomesEast AsianSub1008G=0.532A=0.468
1000GenomesEuropeSub1006G=0.585A=0.415
1000GenomesGlobalStudy-wide5008G=0.561A=0.439
1000GenomesSouth AsianSub978G=0.640A=0.360
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.543A=0.457
The Genome Aggregation DatabaseAfricanSub8698G=0.527A=0.473
The Genome Aggregation DatabaseAmericanSub836G=0.550A=0.450
The Genome Aggregation DatabaseEast AsianSub1606G=0.544A=0.456
The Genome Aggregation DatabaseEuropeSub18470G=0.557A=0.442
The Genome Aggregation DatabaseGlobalStudy-wide29912G=0.548A=0.451
The Genome Aggregation DatabaseOtherSub302G=0.640A=0.360
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.550A=0.449
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.560A=0.440
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs8856850.000109alcohol dependence20201924

eQTL of rs885685 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs885685 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr74890851648908640E067-19657
chr74890869148908779E067-19518
chr74890822148908271E069-20026
chr74890828148908331E069-19966
chr74890822148908271E070-20026
chr74890828148908331E070-19966
chr74890851648908640E070-19657
chr74897353148973623E07045234
chr74890800548908059E071-20238
chr74890822148908271E071-20026
chr74890828148908331E071-19966
chr74890851648908640E071-19657
chr74890768248907770E074-20527
chr74890851648908640E074-19657
chr74890869148908779E074-19518
chr74894226248942486E08113965
chr74894254048942642E08114243
chr74897114648971378E08142849
chr74897353148973623E08145234
chr74890800548908059E082-20238
chr74890822148908271E082-20026
chr74890828148908331E082-19966
chr74894226248942486E08213965
chr74894254048942642E08214243