SNP Detail Info-rs887772

Organism: Homo sapiens

Alleles: T>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0314 (9413/29896,GnomAD)
G=0357 (10419/29118,TOPMED)
G=0356 (1785/5008,1000G)
G=0273 (1054/3854,ALSPAC)
G=0281 (1042/3708,TWINSUK)

Position: chr21:14313131 (GRCh38.p7) (21q11.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 7 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 21	NC_000021.9:g.14313131T>G
GRCh37.p13 chr 21	NC_000021.8:g.15685452T>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	T=0.531	G=0.469
1000Genomes	American	Sub	694	T=0.780	G=0.220
1000Genomes	East Asian	Sub	1008	T=0.632	G=0.368
1000Genomes	Europe	Sub	1006	T=0.722	G=0.278
1000Genomes	Global	Study-wide	5008	T=0.644	G=0.356
1000Genomes	South Asian	Sub	978	T=0.630	G=0.370
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.727	G=0.273
The Genome Aggregation Database	African	Sub	8704	T=0.562	G=0.438
The Genome Aggregation Database	American	Sub	828	T=0.810	G=0.190
The Genome Aggregation Database	East Asian	Sub	1604	T=0.620	G=0.380
The Genome Aggregation Database	Europe	Sub	18458	T=0.743	G=0.257
The Genome Aggregation Database	Global	Study-wide	29896	T=0.685	G=0.314
The Genome Aggregation Database	Other	Sub	302	T=0.720	G=0.280
Trans-Omics for Precision Medicine	Global	Study-wide	29118	T=0.642	G=0.357
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.719	G=0.281

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs887772	0.00078	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr21	15645939	15646819	E067	-38633
chr21	15645939	15646819	E068	-38633
chr21	15645939	15646819	E069	-38633
chr21	15645939	15646819	E071	-38633
chr21	15645939	15646819	E072	-38633
chr21	15645939	15646819	E073	-38633
chr21	15645939	15646819	E074	-38633

rs887772