rs894110

Homo sapiens
C>A / C>G
None
Check p-value
SNV (Single Nucleotide Variation)
C==0475 (14201/29880,GnomAD)
C==0441 (12847/29118,TOPMED)
G=0480 (2402/5008,1000G)
C==0478 (1842/3854,ALSPAC)
C==0493 (1829/3708,TWINSUK)
chr2:129239970 (GRCh38.p7) (2q21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
16 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.129239970C>A
GRCh38.p7 chr 2NC_000002.12:g.129239970C>G
GRCh37.p13 chr 2NC_000002.11:g.129997543C>A
GRCh37.p13 chr 2NC_000002.11:g.129997543C>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.340G=0.660
1000GenomesAmericanSub694C=0.530G=0.470
1000GenomesEast AsianSub1008C=0.767G=0.233
1000GenomesEuropeSub1006C=0.464G=0.536
1000GenomesGlobalStudy-wide5008C=0.520G=0.480
1000GenomesSouth AsianSub978C=0.560G=0.440
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.478G=0.522
The Genome Aggregation DatabaseAfricanSub8696C=0.388G=0.612
The Genome Aggregation DatabaseAmericanSub836C=0.550G=0.450
The Genome Aggregation DatabaseEast AsianSub1620C=0.822G=0.178
The Genome Aggregation DatabaseEuropeSub18426C=0.483G=0.517
The Genome Aggregation DatabaseGlobalStudy-wide29880C=0.475G=0.524
The Genome Aggregation DatabaseOtherSub302C=0.440G=0.560
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.441G=0.558
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.493G=0.507
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs8941107.64E-07alcohol dependence (age at onset)24962325

eQTL of rs894110 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs894110 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2129990903129991022E070-5966
chr2129991443129991904E070-5084
chr2129990903129991022E081-5966
chr2129991443129991904E081-5084
chr2129996773129997036E0810
chr2130010223130010353E08113235
chr2130010398130011293E08113410
chr2130038915130039052E08141927
chr2130039472130039687E08142484
chr2130039843130039996E08142855
chr2129996773129997036E0820
chr2130010223130010353E08213235
chr2130038591130038845E08241603
chr2130038915130039052E08241927
chr2130039472130039687E08242484
chr2130039843130039996E08242855