SNP Detail Info-rs898078

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

LOC105369993 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0241 (7217/29944,GnomAD)
A=0223 (6497/29118,TOPMED)
A=0152 (759/5008,1000G)
A=0293 (1131/3854,ALSPAC)
A=0311 (1154/3708,TWINSUK)

Position: chr12:114025782 (GRCh38.p7) (12q24.21)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 1 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 12	NC_000012.12:g.114025782G>A
GRCh37.p13 chr 12	NC_000012.11:g.114463587G>A

Molecule type	Change	Amino acid[Codon]	SO Term
LOC105369993 transcript variant X1	XR_945351.1:n.	N/A	Intron Variant
LOC105369993 transcript variant X2	XR_945352.1:n.	N/A	Intron Variant
LOC105369993 transcript variant X4	XR_945353.1:n.	N/A	Intron Variant
LOC105369993 transcript variant X5	XR_945355.1:n.	N/A	Intron Variant
LOC105369993 transcript variant X3	XR_945354.1:n.	N/A	Genic Downstream Transcript Variant
LOC105369993 transcript variant X6	XR_945356.1:n.	N/A	Genic Downstream Transcript Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.902	A=0.098
1000Genomes	American	Sub	694	G=0.800	A=0.200
1000Genomes	East Asian	Sub	1008	G=0.981	A=0.019
1000Genomes	Europe	Sub	1006	G=0.712	A=0.288
1000Genomes	Global	Study-wide	5008	G=0.848	A=0.152
1000Genomes	South Asian	Sub	978	G=0.820	A=0.180
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.707	A=0.293
The Genome Aggregation Database	African	Sub	8714	G=0.859	A=0.141
The Genome Aggregation Database	American	Sub	838	G=0.850	A=0.150
The Genome Aggregation Database	East Asian	Sub	1622	G=0.989	A=0.011
The Genome Aggregation Database	Europe	Sub	18470	G=0.688	A=0.312
The Genome Aggregation Database	Global	Study-wide	29944	G=0.759	A=0.241
The Genome Aggregation Database	Other	Sub	300	G=0.720	A=0.280
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.776	A=0.223
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.689	A=0.311

PMID	Title	Author	Journal
21529783	A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.	Heath AC	Biol Psychiatry

SNP ID	p-value	Traits	Study
rs898078	2.5E-05	alcoholism (heaviness of drinking)	21529783

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs898078