rs906071

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0412 (12343/29944,GnomAD)
C=0448 (13053/29118,TOPMED)
C=0374 (1875/5008,1000G)
C=0278 (1073/3854,ALSPAC)
C=0259 (959/3708,TWINSUK)
chr5:10109273 (GRCh38.p7) (5p15.2)
ND
GWASdb2
1   publication(s)
See rs on genome
59 Enhancers around
6 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.10109273T>C
GRCh37.p13 chr 5NC_000005.9:g.10109385T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.258C=0.742
1000GenomesAmericanSub694T=0.690C=0.310
1000GenomesEast AsianSub1008T=0.805C=0.195
1000GenomesEuropeSub1006T=0.686C=0.314
1000GenomesGlobalStudy-wide5008T=0.626C=0.374
1000GenomesSouth AsianSub978T=0.830C=0.170
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.722C=0.278
The Genome Aggregation DatabaseAfricanSub8704T=0.325C=0.675
The Genome Aggregation DatabaseAmericanSub838T=0.690C=0.310
The Genome Aggregation DatabaseEast AsianSub1618T=0.818C=0.182
The Genome Aggregation DatabaseEuropeSub18482T=0.685C=0.315
The Genome Aggregation DatabaseGlobalStudy-wide29944T=0.587C=0.412
The Genome Aggregation DatabaseOtherSub302T=0.710C=0.290
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.551C=0.448
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.741C=0.259
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs9060719.38E-05nicotine smoking19268276

eQTL of rs906071 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs906071 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr51012389310124104E06714508
chr51012444410124750E06715059
chr51012486910124926E06715484
chr51012531210125603E06715927
chr51014067110141036E06731286
chr51014116510141247E06731780
chr51015742310157673E06748038
chr51015786110157951E06748476
chr51012389310124104E06814508
chr51012444410124750E06815059
chr51012486910124926E06815484
chr51012531210125603E06815927
chr51006437210064464E069-44921
chr51006501110065116E069-44269
chr51012389310124104E06914508
chr51012444410124750E06915059
chr51012486910124926E06915484
chr51012531210125603E06915927
chr51014067110141036E06931286
chr51015742310157673E06948038
chr51015786110157951E06948476
chr51006437210064464E070-44921
chr51006501110065116E070-44269
chr51012389310124104E07014508
chr51012444410124750E07015059
chr51012486910124926E07015484
chr51012531210125603E07015927
chr51013881710139001E07029432
chr51006437210064464E071-44921
chr51006501110065116E071-44269
chr51012389310124104E07114508
chr51012444410124750E07115059
chr51012486910124926E07115484
chr51014067110141036E07131286
chr51015742310157673E07148038
chr51012389310124104E07214508
chr51012444410124750E07215059
chr51012486910124926E07215484
chr51012531210125603E07215927
chr51012629510126415E07216910
chr51013407510134198E07224690
chr51014067110141036E07231286
chr51015742310157673E07248038
chr51015786110157951E07248476
chr51013881710139001E07329432
chr51012389310124104E07414508
chr51012444410124750E07415059
chr51012486910124926E07415484
chr51012531210125603E07415927
chr51012629510126415E07416910
chr51014067110141036E07431286
chr51015742310157673E07448038
chr51015786110157951E07448476
chr51012389310124104E08114508
chr51012444410124750E08115059
chr51012486910124926E08115484
chr51013881710139001E08129432
chr51012389310124104E08214508
chr51012444410124750E08215059










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr51013856610138816E06729181
chr51013856610138816E06829181
chr51013856610138816E06929181
chr51013856610138816E07129181
chr51013856610138816E07229181
chr51013856610138816E07429181