rs915175

Organism: Homo sapiens

Alleles: C>T

Gene : Feature

ARMC4 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

C==0309 (9269/29946,GnomAD)
C==0291 (8498/29118,TOPMED)
C==0333 (1666/5008,1000G)
C==0299 (1153/3854,ALSPAC)
C==0309 (1145/3708,TWINSUK)

Position: chr10:27844758 (GRCh38.p7) (10p12.1)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Variant Details Frequency Publications p-values eSNP meSNP

Genomic Coordinates

Sequence Name	Change(s)
GRCh38.p7 chr 10	NC_000010.11:g.27844758C>T
GRCh37.p13 chr 10	NC_000010.10:g.28133687C>T
ARMC4 RefSeqGene	NG_042820.1:g.159293G>A

Gene: ARMC4, armadillo repeat containing 4(minus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
ARMC4 transcript variant 1	NM_001290020.1:c.	N/A	Intron Variant
ARMC4 transcript variant 2	NM_001290021.1:c.	N/A	Intron Variant
ARMC4 transcript variant 4	NM_001312689.1:c.	N/A	Intron Variant
ARMC4 transcript variant 3	NM_018076.4:c.	N/A	Intron Variant
ARMC4 transcript variant X6	XM_011519527.1:c.	N/A	Intron Variant
ARMC4 transcript variant X2	XM_011519528.1:c.	N/A	Intron Variant
ARMC4 transcript variant X6	XM_011519533.2:c.	N/A	Intron Variant
ARMC4 transcript variant X7	XM_011519534.2:c.	N/A	Intron Variant
ARMC4 transcript variant X8	XM_011519535.2:c.	N/A	Intron Variant
ARMC4 transcript variant X10	XM_011519537.2:c.	N/A	Intron Variant
ARMC4 transcript variant X4	XM_017016369.1:c.	N/A	Intron Variant
ARMC4 transcript variant X5	XM_017016370.1:c.	N/A	Intron Variant
ARMC4 transcript variant X3	XM_017016368.1:c.	N/A	Genic Downstream Transcript Variant
ARMC4 transcript variant X11	XM_017016371.1:c.	N/A	Genic Downstream Transcript Variant

Population Frequency

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	C=0.312	T=0.688
1000Genomes	American	Sub	694	C=0.320	T=0.680
1000Genomes	East Asian	Sub	1008	C=0.450	T=0.550
1000Genomes	Europe	Sub	1006	C=0.268	T=0.732
1000Genomes	Global	Study-wide	5008	C=0.333	T=0.667
1000Genomes	South Asian	Sub	978	C=0.320	T=0.680
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.299	T=0.701
The Genome Aggregation Database	African	Sub	8712	C=0.319	T=0.681
The Genome Aggregation Database	American	Sub	838	C=0.360	T=0.640
The Genome Aggregation Database	East Asian	Sub	1608	C=0.396	T=0.604
The Genome Aggregation Database	Europe	Sub	18486	C=0.296	T=0.703
The Genome Aggregation Database	Global	Study-wide	29946	C=0.309	T=0.690
The Genome Aggregation Database	Other	Sub	302	C=0.260	T=0.740
Trans-Omics for Precision Medicine	Global	Study-wide	29118	C=0.291	T=0.708
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=0.309	T=0.691

PMID	Title	Author	Journal
19268276	Genome-wide association study of smoking initiation and current smoking.	Vink JM	Am J Hum Genet

P-Value

SNP ID	p-value	Traits	Study
rs915175	0.000509	nicotine smoking	19268276

eQTL of rs915175 in Brain tissues (GTEx Analysis Release V7)

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

meQTL of rs915175 in Fetal Brain

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.