rs919888

Homo sapiens
C>A / C>G
LOC107984245 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0403 (12067/29900,GnomAD)
G=0427 (12442/29118,TOPMED)
G=0497 (2489/5008,1000G)
G=0337 (1297/3854,ALSPAC)
G=0342 (1269/3708,TWINSUK)
chr10:78455530 (GRCh38.p7) (10q22.3)
ND
GWASdb2
1   publication(s)
See rs on genome
113 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.78455530C>A
GRCh38.p7 chr 10NC_000010.11:g.78455530C>G
GRCh37.p13 chr 10NC_000010.10:g.80215287C>A
GRCh37.p13 chr 10NC_000010.10:g.80215287C>G

Gene: LOC107984245, uncharacterized LOC107984245(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC107984245 transcriptXR_001747513.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.434G=0.566
1000GenomesAmericanSub694C=0.590G=0.410
1000GenomesEast AsianSub1008C=0.419G=0.581
1000GenomesEuropeSub1006C=0.640G=0.360
1000GenomesGlobalStudy-wide5008C=0.503G=0.497
1000GenomesSouth AsianSub978C=0.480G=0.520
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.663G=0.337
The Genome Aggregation DatabaseAfricanSub8698C=0.489A=0.000
The Genome Aggregation DatabaseAmericanSub836C=0.640A=0.00,
The Genome Aggregation DatabaseEast AsianSub1618C=0.419A=0.000
The Genome Aggregation DatabaseEuropeSub18446C=0.660A=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29900C=0.596A=0.000
The Genome Aggregation DatabaseOtherSub302C=0.610A=0.00,
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.572G=0.427
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.658G=0.342
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs9198880.000217nicotine dependence17158188

eQTL of rs919888 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs919888 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr103549748635497987E067-24050
chr103549883835499075E067-22962
chr103549912835499324E067-22713
chr103549961235499679E067-22358
chr103549986835500094E067-21943
chr103550011635500732E067-21305
chr103550511735505891E067-16146
chr103550590735505974E067-16063
chr103550613435506196E067-15841
chr103550628335506741E067-15296
chr103550706535507919E067-14118
chr103548040635480825E068-41212
chr103548084135480979E068-41058
chr103548100735481068E068-40969
chr103548108835481205E068-40832
chr103549748635497987E068-24050
chr103549820635498449E068-23588
chr103549853635498576E068-23461
chr103549883835499075E068-22962
chr103549912835499324E068-22713
chr103549961235499679E068-22358
chr103550498235505036E068-17001
chr103550511735505891E068-16146
chr103550590735505974E068-16063
chr103550613435506196E068-15841
chr103550628335506741E068-15296
chr103550684335506965E068-15072
chr103550706535507919E068-14118
chr103549748635497987E069-24050
chr103549820635498449E069-23588
chr103549853635498576E069-23461
chr103549883835499075E069-22962
chr103549912835499324E069-22713
chr103549961235499679E069-22358
chr103550498235505036E069-17001
chr103550511735505891E069-16146
chr103550590735505974E069-16063
chr103550613435506196E069-15841
chr103550628335506741E069-15296
chr103550684335506965E069-15072
chr103550706535507919E069-14118
chr103552153135521678E069-359
chr103552168935521900E069-137
chr103550590735505974E070-16063
chr103548040635480825E071-41212
chr103548084135480979E071-41058
chr103548100735481068E071-40969
chr103548108835481205E071-40832
chr103549748635497987E071-24050
chr103549820635498449E071-23588
chr103549853635498576E071-23461
chr103549883835499075E071-22962
chr103549912835499324E071-22713
chr103549961235499679E071-22358
chr103550011635500732E071-21305
chr103550511735505891E071-16146
chr103550590735505974E071-16063
chr103550613435506196E071-15841
chr103550706535507919E071-14118
chr103550793935507989E071-14048
chr103554159635541698E07119559
chr103548084135480979E072-41058
chr103548100735481068E072-40969
chr103548108835481205E072-40832
chr103549820635498449E072-23588
chr103549853635498576E072-23461
chr103549961235499679E072-22358
chr103550511735505891E072-16146
chr103550590735505974E072-16063
chr103550613435506196E072-15841
chr103550628335506741E072-15296
chr103550684335506965E072-15072
chr103550706535507919E072-14118
chr103552153135521678E072-359
chr103552168935521900E072-137
chr103548040635480825E073-41212
chr103548084135480979E073-41058
chr103548100735481068E073-40969
chr103548108835481205E073-40832
chr103548146435481514E073-40523
chr103549748635497987E073-24050
chr103549820635498449E073-23588
chr103549986835500094E073-21943
chr103550278335502937E073-19100
chr103550298235503032E073-19005
chr103550311635503192E073-18845
chr103550339035503783E073-18254
chr103550511735505891E073-16146
chr103550628335506741E073-15296
chr103550684335506965E073-15072
chr103550706535507919E073-14118
chr103549748635497987E074-24050
chr103549820635498449E074-23588
chr103549853635498576E074-23461
chr103549883835499075E074-22962
chr103549912835499324E074-22713
chr103549961235499679E074-22358
chr103549986835500094E074-21943
chr103550011635500732E074-21305
chr103550511735505891E074-16146
chr103550590735505974E074-16063
chr103550613435506196E074-15841
chr103550628335506741E074-15296
chr103550684335506965E074-15072
chr103550706535507919E074-14118
chr103549275335493137E081-28900
chr103549344135493518E081-28519
chr103550145335501598E081-20439
chr103550268735502739E081-19298
chr103550278335502937E081-19100
chr103550298235503032E081-19005
chr103550311635503192E081-18845
chr103550339035503783E081-18254









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr103548383135485796E067-36241
chr103548383135485796E068-36241
chr103548383135485796E069-36241
chr103548383135485796E070-36241
chr103548383135485796E071-36241
chr103548383135485796E072-36241
chr103548383135485796E073-36241
chr103548383135485796E074-36241
chr103548383135485796E081-36241
chr103548383135485796E082-36241