rs9284846

Homo sapiens
G>T
LOC105376976 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0257 (7673/29762,GnomAD)
T=0233 (6787/29118,TOPMED)
T=0231 (1158/5008,1000G)
T=0274 (1055/3854,ALSPAC)
T=0284 (1052/3708,TWINSUK)
chr3:18749210 (GRCh38.p7) (3p24.3)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.18749210G>T
GRCh37.p13 chr 3NC_000003.11:g.18790702G>T

Gene: LOC105376976, uncharacterized LOC105376976(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105376976 transcript variant X2XR_001740423.1:n.N/AIntron Variant
LOC105376976 transcript variant X1XR_940635.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.801T=0.199
1000GenomesAmericanSub694G=0.800T=0.200
1000GenomesEast AsianSub1008G=0.696T=0.304
1000GenomesEuropeSub1006G=0.766T=0.234
1000GenomesGlobalStudy-wide5008G=0.769T=0.231
1000GenomesSouth AsianSub978G=0.780T=0.220
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.726T=0.274
The Genome Aggregation DatabaseAfricanSub8706G=0.794T=0.206
The Genome Aggregation DatabaseAmericanSub832G=0.760T=0.240
The Genome Aggregation DatabaseEast AsianSub1518G=0.734T=0.266
The Genome Aggregation DatabaseEuropeSub18406G=0.716T=0.283
The Genome Aggregation DatabaseGlobalStudy-wide29762G=0.742T=0.257
The Genome Aggregation DatabaseOtherSub300G=0.810T=0.190
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.766T=0.233
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.716T=0.284
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs92848460.00098alcohol dependence20201924

eQTL of rs9284846 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9284846 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr31879497518795066E0814273
chr31879497518795066E0824273