rs9292042

Homo sapiens
C>T
ARL15 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C==0353 (10550/29886,GnomAD)
C==0368 (10731/29118,TOPMED)
C==0433 (2169/5008,1000G)
C==0314 (1210/3854,ALSPAC)
C==0310 (1150/3708,TWINSUK)
chr5:54241168 (GRCh38.p7) (5q11.2)
AD
GWASdb2
1   publication(s)
See rs on genome
14 Enhancers around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.54241168C>T
GRCh37.p13 chr 5NC_000005.9:g.53536998C>T

Gene: ARL15, ADP ribosylation factor like GTPase 15(minus strand)

Molecule type Change Amino acid[Codon] SO Term
ARL15 transcriptNM_019087.2:c.N/AIntron Variant
ARL15 transcript variant X1XM_011543498.2:c.N/AIntron Variant
ARL15 transcript variant X2XM_011543499.2:c.N/AIntron Variant
ARL15 transcript variant X3XM_011543500.2:c.N/AIntron Variant
ARL15 transcript variant X4XM_017009598.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.425T=0.575
1000GenomesAmericanSub694C=0.530T=0.470
1000GenomesEast AsianSub1008C=0.573T=0.427
1000GenomesEuropeSub1006C=0.311T=0.689
1000GenomesGlobalStudy-wide5008C=0.433T=0.567
1000GenomesSouth AsianSub978C=0.350T=0.650
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.314T=0.686
The Genome Aggregation DatabaseAfricanSub8698C=0.408T=0.592
The Genome Aggregation DatabaseAmericanSub834C=0.510T=0.490
The Genome Aggregation DatabaseEast AsianSub1610C=0.602T=0.398
The Genome Aggregation DatabaseEuropeSub18442C=0.299T=0.700
The Genome Aggregation DatabaseGlobalStudy-wide29886C=0.353T=0.647
The Genome Aggregation DatabaseOtherSub302C=0.240T=0.760
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.368T=0.631
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.310T=0.690
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs92920424.69E-07alcohol dependence (age at onset)24962325

eQTL of rs9292042 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9292042 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr55352492153525456E068-11542
chr55357394153574185E06936943
chr55357422253574433E06937224
chr55351066653510874E070-26124
chr55351115053511650E070-25348
chr55351327153513323E070-23675
chr55357394153574185E07236943
chr55357422253574433E07237224
chr55357444553574505E07237447
chr55357422253574433E07437224
chr55357444553574505E07437447
chr55351066653510874E081-26124
chr55351115053511650E081-25348
chr55351115053511650E082-25348







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr55355060653550896E07113608