rs9297181

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0211 (6308/29888,GnomAD)
A=0233 (6795/29118,TOPMED)
A=0236 (1183/5008,1000G)
A=0184 (711/3854,ALSPAC)
A=0193 (714/3708,TWINSUK)
chr8:30019089 (GRCh38.p7) (8p12)
AD
GWASdb2
2   publication(s)
See rs on genome
62 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.30019089G>A
GRCh37.p13 chr 8NC_000008.10:g.29876605G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.671A=0.329
1000GenomesAmericanSub694G=0.850A=0.150
1000GenomesEast AsianSub1008G=0.713A=0.287
1000GenomesEuropeSub1006G=0.806A=0.194
1000GenomesGlobalStudy-wide5008G=0.764A=0.236
1000GenomesSouth AsianSub978G=0.840A=0.160
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.816A=0.184
The Genome Aggregation DatabaseAfricanSub8680G=0.710A=0.290
The Genome Aggregation DatabaseAmericanSub836G=0.840A=0.160
The Genome Aggregation DatabaseEast AsianSub1614G=0.654A=0.346
The Genome Aggregation DatabaseEuropeSub18456G=0.835A=0.164
The Genome Aggregation DatabaseGlobalStudy-wide29888G=0.788A=0.211
The Genome Aggregation DatabaseOtherSub302G=0.800A=0.200
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.766A=0.233
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.807A=0.193
PMID Title Author Journal
17903298Genome-wide association with diabetes-related traits in the Framingham Heart Study.Meigs JBBMC Med Genet
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs92971810.00037alcohol dependence24277619

eQTL of rs9297181 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9297181 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr82992398229924210E06747377
chr82992438229924439E06747777
chr82992448029924770E06747875
chr82992477329924898E06748168
chr82992500929925087E06748404
chr82992511529925218E06748510
chr82992523329925395E06748628
chr82992546829925778E06748863
chr82983415629834206E068-42399
chr82983428329834638E068-41967
chr82985789329858072E068-18533
chr82985810729858648E068-17957
chr82992448029924770E06847875
chr82992477329924898E06848168
chr82992500929925087E06848404
chr82992511529925218E06848510
chr82985810729858648E070-17957
chr82985874529858860E070-17745
chr82985896129859011E070-17594
chr82987809829878152E0701493
chr82987834629878509E0701741
chr82986977629869849E071-6756
chr82986987829870269E071-6336
chr82992500929925087E07248404
chr82992511529925218E07248510
chr82992523329925395E07248628
chr82992546829925778E07248863
chr82984584129845894E081-30711
chr82984673929847042E081-29563
chr82984704429847187E081-29418
chr82984768229847742E081-28863
chr82984775129848026E081-28579
chr82984814329849150E081-27455
chr82985789329858072E081-18533
chr82985810729858648E081-17957
chr82985874529858860E081-17745
chr82985896129859011E081-17594
chr82986897129869044E081-7561
chr82986910129869378E081-7227
chr82986940529869476E081-7129
chr82986977629869849E081-6756
chr82986987829870269E081-6336
chr82987045829870508E081-6097
chr82987683329876883E081228
chr82987690629876997E081301
chr82987722229878067E081617
chr82987809829878152E0811493
chr82987834629878509E0811741
chr82984656829846688E082-29917
chr82984673929847042E082-29563
chr82984775129848026E082-28579
chr82984814329849150E082-27455
chr82985810729858648E082-17957
chr82985874529858860E082-17745
chr82986004629860148E082-16457
chr82986940529869476E082-7129
chr82986977629869849E082-6756
chr82986987829870269E082-6336
chr82987144629872040E082-4565
chr82987722229878067E082617
chr82987809829878152E0821493
chr82987884729878923E0822242