rs9308631

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
G==0348 (10412/29904,GnomAD)
G==0315 (9190/29116,TOPMED)
G==0348 (1741/5008,1000G)
G==0394 (1519/3854,ALSPAC)
G==0384 (1423/3708,TWINSUK)
chr2:111684854 (GRCh38.p7) (2q13)
ND
GWASdb2
1   publication(s)
See rs on genome
30 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.111684854G>A
GRCh37.p13 chr 2NC_000002.11:g.112442431G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.226A=0.774
1000GenomesAmericanSub694G=0.350A=0.650
1000GenomesEast AsianSub1008G=0.419A=0.581
1000GenomesEuropeSub1006G=0.379A=0.621
1000GenomesGlobalStudy-wide5008G=0.348A=0.652
1000GenomesSouth AsianSub978G=0.400A=0.600
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.394A=0.606
The Genome Aggregation DatabaseAfricanSub8696G=0.248A=0.752
The Genome Aggregation DatabaseAmericanSub838G=0.390A=0.610
The Genome Aggregation DatabaseEast AsianSub1614G=0.398A=0.602
The Genome Aggregation DatabaseEuropeSub18454G=0.388A=0.611
The Genome Aggregation DatabaseGlobalStudy-wide29904G=0.348A=0.651
The Genome Aggregation DatabaseOtherSub302G=0.350A=0.650
Trans-Omics for Precision MedicineGlobalStudy-wide29116G=0.315A=0.684
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.384A=0.616
PMID Title Author Journal
22377092ANAPC1 and SLCO3A1 are associated with nicotine dependence: meta-analysis of genome-wide association studies.Wang KSDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs93086317.25E-06nicotine dependence (smoking)22377092

eQTL of rs9308631 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9308631 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2112462901112464321E07020470
chr2112464516112464643E07022085
chr2112433581112433731E072-8700
chr2112419497112419604E081-22827
chr2112419728112420435E081-21996
chr2112420457112420513E081-21918
chr2112420740112420891E081-21540
chr2112433352112433490E081-8941
chr2112433581112433731E081-8700
chr2112434054112434302E081-8129
chr2112434448112434529E081-7902
chr2112435017112435057E081-7374
chr2112435151112435211E081-7220
chr2112435485112435572E081-6859
chr2112435883112436108E081-6323
chr2112436209112436591E081-5840
chr2112436641112436704E081-5727
chr2112436753112437061E081-5370
chr2112449091112449472E0816660
chr2112449553112449603E0817122
chr2112449709112449759E0817278
chr2112449868112450073E0817437
chr2112456326112457104E08113895
chr2112462901112464321E08120470
chr2112465304112465370E08122873
chr2112466166112466234E08123735
chr2112466329112466623E08123898
chr2112436209112436591E082-5840
chr2112456326112457104E08213895
chr2112462901112464321E08220470