rs9343705

Homo sapiens
C>T
LOC105377865 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C==0283 (8476/29898,GnomAD)
C==0265 (7739/29118,TOPMED)
C==0239 (1198/5008,1000G)
C==0353 (1360/3854,ALSPAC)
C==0348 (1289/3708,TWINSUK)
chr6:77985773 (GRCh38.p7) (6q14.1)
CD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.77985773C>T
GRCh37.p13 chr 6NC_000006.11:g.78695490C>T

Gene: LOC105377865, uncharacterized LOC105377865(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105377865 transcript variant X1XR_942710.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.174T=0.826
1000GenomesAmericanSub694C=0.250T=0.750
1000GenomesEast AsianSub1008C=0.127T=0.873
1000GenomesEuropeSub1006C=0.307T=0.693
1000GenomesGlobalStudy-wide5008C=0.239T=0.761
1000GenomesSouth AsianSub978C=0.370T=0.630
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.353T=0.647
The Genome Aggregation DatabaseAfricanSub8696C=0.201T=0.799
The Genome Aggregation DatabaseAmericanSub832C=0.240T=0.760
The Genome Aggregation DatabaseEast AsianSub1608C=0.152T=0.848
The Genome Aggregation DatabaseEuropeSub18464C=0.335T=0.664
The Genome Aggregation DatabaseGlobalStudy-wide29898C=0.283T=0.716
The Genome Aggregation DatabaseOtherSub298C=0.280T=0.720
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.265T=0.734
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.348T=0.652
PMID Title Author Journal
23958962Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.Gelernter JMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs93437053.75E-05cocaine dependence23958962

eQTL of rs9343705 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9343705 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.