rs9350404

Homo sapiens
A>G
CASC15 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0392 (11669/29760,GnomAD)
G=0358 (10437/29118,TOPMED)
G=0318 (1592/5008,1000G)
A==0437 (1685/3854,ALSPAC)
A==0442 (1639/3708,TWINSUK)
chr6:21994515 (GRCh38.p7) (6p22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
113 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.21994515A>G
GRCh37.p13 chr 6NC_000006.11:g.21994744A>G

Gene: CASC15, cancer susceptibility candidate 15 (non-protein coding)(plus strand)

Molecule type Change Amino acid[Codon] SO Term
CASC15 transcriptNR_015410.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.900G=0.100
1000GenomesAmericanSub694A=0.640G=0.360
1000GenomesEast AsianSub1008A=0.817G=0.183
1000GenomesEuropeSub1006A=0.500G=0.500
1000GenomesGlobalStudy-wide5008A=0.682G=0.318
1000GenomesSouth AsianSub978A=0.470G=0.530
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.437G=0.563
The Genome Aggregation DatabaseAfricanSub8638A=0.835G=0.165
The Genome Aggregation DatabaseAmericanSub832A=0.650G=0.350
The Genome Aggregation DatabaseEast AsianSub1610A=0.809G=0.191
The Genome Aggregation DatabaseEuropeSub18380A=0.481G=0.518
The Genome Aggregation DatabaseGlobalStudy-wide29760A=0.607G=0.392
The Genome Aggregation DatabaseOtherSub300A=0.610G=0.390
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.641G=0.358
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.442G=0.558
PMID Title Author Journal
23953852Genome-wide association studies of maximum number of drinks.Pan YJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs93504046.26E-05alcohol consumption23953852

eQTL of rs9350404 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9350404 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr62195091021951926E068-42818
chr62195194921952206E068-42538
chr62198706921987266E068-7478
chr62198727821987402E068-7342
chr62202859122028990E06833847
chr62202902922029334E06834285
chr62202938022029854E06834636
chr62204347222044081E06848728
chr62195091021951926E070-42818
chr62195194921952206E070-42538
chr62195223721952290E070-42454
chr62196762621967753E070-26991
chr62196780121967907E070-26837
chr62196795021968144E070-26600
chr62197114121971546E070-23198
chr62197180521972052E070-22692
chr62198473021985143E070-9601
chr62198518621985298E070-9446
chr62199134221991637E070-3107
chr62199178421991847E070-2897
chr62199190621991956E070-2788
chr62199227021992440E070-2304
chr62199247521992691E070-2053
chr62199346121993534E070-1210
chr62199762021998207E0702876
chr62199844621998564E0703702
chr62199871721999915E0703973
chr62202401822024771E07029274
chr62202483322024883E07030089
chr62202535522026633E07030611
chr62202670822026777E07031964
chr62202902922029334E07034285
chr62202938022029854E07034636
chr62195091021951926E071-42818
chr62204347222044081E07248728
chr62195091021951926E073-42818
chr62195194921952206E073-42538
chr62198706921987266E074-7478
chr62198727821987402E074-7342
chr62202902922029334E07434285
chr62202938022029854E07434636
chr62195091021951926E081-42818
chr62195194921952206E081-42538
chr62195373021953867E081-40877
chr62195398421954994E081-39750
chr62195533621955606E081-39138
chr62196780121967907E081-26837
chr62196795021968144E081-26600
chr62197114121971546E081-23198
chr62197180521972052E081-22692
chr62197206921972172E081-22572
chr62197221421972294E081-22450
chr62197758621977833E081-16911
chr62198449921984729E081-10015
chr62198473021985143E081-9601
chr62198518621985298E081-9446
chr62198706921987266E081-7478
chr62198727821987402E081-7342
chr62198747821988184E081-6560
chr62199070021991202E081-3542
chr62199134221991637E081-3107
chr62199178421991847E081-2897
chr62199190621991956E081-2788
chr62199686821997491E0812124
chr62199762021998207E0812876
chr62199844621998564E0813702
chr62199871721999915E0813973
chr62200041322000562E0815669
chr62200069822000762E0815954
chr62200099822001048E0816254
chr62200146122001862E0816717
chr62200189922002065E0817155
chr62202401822024771E08129274
chr62202902922029334E08134285
chr62202938022029854E08134636
chr62202989722030019E08135153
chr62203002022030108E08135276
chr62194942521950071E082-44673
chr62195290621952966E082-41778
chr62195300121953045E082-41699
chr62195398421954994E082-39750
chr62195533621955606E082-39138
chr62195701321957188E082-37556
chr62196633621966633E082-28111
chr62196738221967504E082-27240
chr62196762621967753E082-26991
chr62196780121967907E082-26837
chr62196795021968144E082-26600
chr62197758621977833E082-16911
chr62198518621985298E082-9446
chr62199134221991637E082-3107
chr62199178421991847E082-2897
chr62199190621991956E082-2788
chr62199227021992440E082-2304
chr62199247521992691E082-2053
chr62199589021996382E0821146
chr62199762021998207E0822876
chr62199844621998564E0823702
chr62199871721999915E0823973
chr62200041322000562E0825669
chr62200069822000762E0825954
chr62200099822001048E0826254
chr62200146122001862E0826717
chr62200189922002065E0827155
chr62200355322003814E0828809
chr62202401822024771E08229274
chr62202535522026633E08230611
chr62202670822026777E08231964
chr62202859122028990E08233847
chr62202902922029334E08234285
chr62202938022029854E08234636
chr62202989722030019E08235153
chr62203002022030108E08235276