rs935085

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0474 (14149/29838,GnomAD)
T==0440 (12825/29118,TOPMED)
C=0480 (2402/5008,1000G)
T==0477 (1840/3854,ALSPAC)
T==0493 (1827/3708,TWINSUK)
chr2:129240460 (GRCh38.p7) (2q21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
16 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.129240460T>C
GRCh37.p13 chr 2NC_000002.11:g.129998033T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.340C=0.660
1000GenomesAmericanSub694T=0.530C=0.470
1000GenomesEast AsianSub1008T=0.767C=0.233
1000GenomesEuropeSub1006T=0.464C=0.536
1000GenomesGlobalStudy-wide5008T=0.520C=0.480
1000GenomesSouth AsianSub978T=0.560C=0.440
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.477C=0.523
The Genome Aggregation DatabaseAfricanSub8686T=0.386C=0.614
The Genome Aggregation DatabaseAmericanSub836T=0.550C=0.450
The Genome Aggregation DatabaseEast AsianSub1614T=0.820C=0.180
The Genome Aggregation DatabaseEuropeSub18400T=0.482C=0.517
The Genome Aggregation DatabaseGlobalStudy-wide29838T=0.474C=0.525
The Genome Aggregation DatabaseOtherSub302T=0.440C=0.560
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.440C=0.559
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.493C=0.507
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs9350857.64E-07alcohol dependence (age at onset)24962325

eQTL of rs935085 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs935085 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2129990903129991022E070-7011
chr2129991443129991904E070-6129
chr2129990903129991022E081-7011
chr2129991443129991904E081-6129
chr2129996773129997036E081-997
chr2130010223130010353E08112190
chr2130010398130011293E08112365
chr2130038915130039052E08140882
chr2130039472130039687E08141439
chr2130039843130039996E08141810
chr2129996773129997036E082-997
chr2130010223130010353E08212190
chr2130038591130038845E08240558
chr2130038915130039052E08240882
chr2130039472130039687E08241439
chr2130039843130039996E08241810