rs935549

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0346 (10349/29912,GnomAD)
C==0283 (1415/5008,1000G)
C==0393 (1513/3854,ALSPAC)
C==0387 (1434/3708,TWINSUK)
chr15:57581240 (GRCh38.p7) (15q21.3)
AD
GWASdb2
1   publication(s)
See rs on genome
108 Enhancers around
8 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.57581240C>T
GRCh37.p13 chr 15NC_000015.9:g.57873438C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.238T=0.762
1000GenomesAmericanSub694C=0.370T=0.630
1000GenomesEast AsianSub1008C=0.111T=0.889
1000GenomesEuropeSub1006C=0.406T=0.594
1000GenomesGlobalStudy-wide5008C=0.283T=0.717
1000GenomesSouth AsianSub978C=0.330T=0.670
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.393T=0.607
The Genome Aggregation DatabaseAfricanSub8704C=0.239T=0.761
The Genome Aggregation DatabaseAmericanSub838C=0.370T=0.630
The Genome Aggregation DatabaseEast AsianSub1620C=0.114T=0.886
The Genome Aggregation DatabaseEuropeSub18448C=0.416T=0.583
The Genome Aggregation DatabaseGlobalStudy-wide29912C=0.346T=0.654
The Genome Aggregation DatabaseOtherSub302C=0.280T=0.720
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.387T=0.613
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs9355490.0000039alcohol dependence(early age of onset)20201924
rs9355490.00000391alcoholismpha002892
rs9355490.00017alcohol dependence20201924

eQTL of rs935549 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs935549 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr155782908957829608E067-43830
chr155782965057829700E067-43738
chr155782984757829924E067-43514
chr155782993157830010E067-43428
chr155784641257847278E067-26160
chr155784735557847395E067-26043
chr155784740457847978E067-25460
chr155791899557919271E06745557
chr155782472657824841E068-48597
chr155782491657825041E068-48397
chr155782516557826377E068-47061
chr155782643957826838E068-46600
chr155782693257827022E068-46416
chr155782723657827344E068-46094
chr155782898257829072E068-44366
chr155782908957829608E068-43830
chr155782965057829700E068-43738
chr155782984757829924E068-43514
chr155782993157830010E068-43428
chr155783014957830243E068-43195
chr155783034057830559E068-42879
chr155784199657842564E068-30874
chr155784274157843198E068-30240
chr155784326857843462E068-29976
chr155784525757845392E068-28046
chr155784543757845509E068-27929
chr155784553357846018E068-27420
chr155784602257846166E068-27272
chr155784641257847278E068-26160
chr155784735557847395E068-26043
chr155784740457847978E068-25460
chr155788099057881070E0687552
chr155788118357881273E0687745
chr155788134457881423E0687906
chr155791899557919271E06845557
chr155782516557826377E069-47061
chr155782908957829608E069-43830
chr155784199657842564E069-30874
chr155784326857843462E069-29976
chr155784553357846018E069-27420
chr155784602257846166E069-27272
chr155784641257847278E069-26160
chr155784735557847395E069-26043
chr155789644757897249E06923009
chr155782516557826377E070-47061
chr155784641257847278E070-26160
chr155791865757918798E07045219
chr155791899557919271E07045557
chr155782491657825041E071-48397
chr155782516557826377E071-47061
chr155782643957826838E071-46600
chr155782693257827022E071-46416
chr155782898257829072E071-44366
chr155782908957829608E071-43830
chr155784274157843198E071-30240
chr155784326857843462E071-29976
chr155784495157845186E071-28252
chr155784543757845509E071-27929
chr155784553357846018E071-27420
chr155784602257846166E071-27272
chr155784641257847278E071-26160
chr155784735557847395E071-26043
chr155784740457847978E071-25460
chr155788155357882255E0718115
chr155788225657882367E0718818
chr155789644757897249E07123009
chr155782516557826377E072-47061
chr155782908957829608E072-43830
chr155782965057829700E072-43738
chr155782984757829924E072-43514
chr155782993157830010E072-43428
chr155783014957830243E072-43195
chr155783034057830559E072-42879
chr155783436057834902E072-38536
chr155784602257846166E072-27272
chr155784641257847278E072-26160
chr155784735557847395E072-26043
chr155784740457847978E072-25460
chr155782516557826377E073-47061
chr155782898257829072E073-44366
chr155782908957829608E073-43830
chr155784326857843462E073-29976
chr155784349557843896E073-29542
chr155784553357846018E073-27420
chr155784602257846166E073-27272
chr155784641257847278E073-26160
chr155789644757897249E07323009
chr155782491657825041E074-48397
chr155782516557826377E074-47061
chr155782984757829924E074-43514
chr155784641257847278E074-26160
chr155784735557847395E074-26043
chr155784740457847978E074-25460
chr155785897757859508E074-13930
chr155788055857880944E0747120
chr155788099057881070E0747552
chr155788118357881273E0747745
chr155788134457881423E0747906
chr155791196257912302E07438524
chr155791232757912407E07438889
chr155791899557919271E07445557
chr155783418957834348E081-39090
chr155783436057834902E081-38536
chr155784641257847278E081-26160
chr155784602257846166E082-27272
chr155784641257847278E082-26160
chr155784735557847395E082-26043
chr155784740457847978E082-25460










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr155788335657885099E0679918
chr155788335657885099E0689918
chr155788335657885099E0699918
chr155788335657885099E0719918
chr155788335657885099E0729918
chr155788335657885099E0739918
chr155788335657885099E0749918
chr155788335657885099E0829918