SNP Detail Info-rs9357585

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G==0317 (9452/29790,GnomAD)
G==0318 (9282/29118,TOPMED)
G==0390 (1953/5008,1000G)
G==0320 (1234/3854,ALSPAC)
G==0312 (1158/3708,TWINSUK)

Position: chr6:48895241 (GRCh38.p7) (6p12.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 1 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 6	NC_000006.12:g.48895241G>A
GRCh37.p13 chr 6	NC_000006.11:g.48862878G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.269	A=0.731
1000Genomes	American	Sub	694	G=0.530	A=0.470
1000Genomes	East Asian	Sub	1008	G=0.536	A=0.464
1000Genomes	Europe	Sub	1006	G=0.318	A=0.682
1000Genomes	Global	Study-wide	5008	G=0.390	A=0.610
1000Genomes	South Asian	Sub	978	G=0.370	A=0.630
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.320	A=0.680
The Genome Aggregation Database	African	Sub	8720	G=0.266	A=0.734
The Genome Aggregation Database	American	Sub	830	G=0.570	A=0.430
The Genome Aggregation Database	East Asian	Sub	1560	G=0.537	A=0.463
The Genome Aggregation Database	Europe	Sub	18380	G=0.312	A=0.687
The Genome Aggregation Database	Global	Study-wide	29790	G=0.317	A=0.682
The Genome Aggregation Database	Other	Sub	300	G=0.270	A=0.730
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.318	A=0.681
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.312	A=0.688

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs9357585	0.000689	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
Chr6:48862878	CENPQ	ENSG00000031691.6	G>A	2.1548e-12	-568213	Cortex
Chr6:48862878	C6orf141	ENSG00000197261.7	G>A	3.4487e-9	-655235	Cerebellar_Hemisphere

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs9357585