rs9367338

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0325 (9748/29918,GnomAD)
C==0331 (9653/29118,TOPMED)
C==0391 (1960/5008,1000G)
C==0323 (1244/3854,ALSPAC)
C==0314 (1166/3708,TWINSUK)
chr6:48982301 (GRCh38.p7) (6p12.3)
AD
GWASdb2
1   publication(s)
See rs on genome
4 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.48982301C>T
GRCh37.p13 chr 6NC_000006.11:g.48949938C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.295T=0.705
1000GenomesAmericanSub694C=0.540T=0.460
1000GenomesEast AsianSub1008C=0.496T=0.504
1000GenomesEuropeSub1006C=0.325T=0.675
1000GenomesGlobalStudy-wide5008C=0.391T=0.609
1000GenomesSouth AsianSub978C=0.380T=0.620
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.323T=0.677
The Genome Aggregation DatabaseAfricanSub8706C=0.285T=0.715
The Genome Aggregation DatabaseAmericanSub836C=0.570T=0.430
The Genome Aggregation DatabaseEast AsianSub1610C=0.507T=0.493
The Genome Aggregation DatabaseEuropeSub18464C=0.319T=0.680
The Genome Aggregation DatabaseGlobalStudy-wide29918C=0.325T=0.674
The Genome Aggregation DatabaseOtherSub302C=0.260T=0.740
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.331T=0.668
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.314T=0.686
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs93673380.000239alcohol dependence20201924

eQTL of rs9367338 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
Chr6:48949938CENPQENSG00000031691.6C>T5.7279e-16-481153Frontal_Cortex_BA9
Chr6:48949938CENPQENSG00000031691.6C>T2.1548e-12-481153Cortex
Chr6:48949938C6orf141ENSG00000197261.7C>T3.4487e-9-568175Cerebellar_Hemisphere

meQTL of rs9367338 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr64896943048970063E07019492
chr64896943048970063E07419492
chr64896943048970063E08119492
chr64897012648970409E08120188