rs939144

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
G==0466 (13914/29832,GnomAD)
G==0434 (12659/29118,TOPMED)
G==0386 (1931/5008,1000G)
G==0470 (1812/3854,ALSPAC)
G==0458 (1699/3708,TWINSUK)
chr8:120967417 (GRCh38.p7) (8q24.12)
AD
GWASdb2
1   publication(s)
See rs on genome
36 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.120967417G>A
GRCh37.p13 chr 8NC_000008.10:g.121979657G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.457A=0.543
1000GenomesAmericanSub694G=0.390A=0.610
1000GenomesEast AsianSub1008G=0.324A=0.676
1000GenomesEuropeSub1006G=0.456A=0.544
1000GenomesGlobalStudy-wide5008G=0.386A=0.614
1000GenomesSouth AsianSub978G=0.270A=0.730
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.470A=0.530
The Genome Aggregation DatabaseAfricanSub8686G=0.465A=0.535
The Genome Aggregation DatabaseAmericanSub834G=0.370A=0.630
The Genome Aggregation DatabaseEast AsianSub1606G=0.307A=0.693
The Genome Aggregation DatabaseEuropeSub18406G=0.485A=0.514
The Genome Aggregation DatabaseGlobalStudy-wide29832G=0.466A=0.533
The Genome Aggregation DatabaseOtherSub300G=0.440A=0.560
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.434A=0.565
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.458A=0.542
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs9391440.00016alcohol dependence(early age of onset)20201924
rs9391440.00072alcohol dependence20201924

eQTL of rs939144 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs939144 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8121945002121945454E068-34203
chr8121945502121945872E068-33785
chr8121945920121946003E068-33654
chr8121946044121946162E068-33495
chr8121946193121946251E068-33406
chr8121945502121945872E069-33785
chr8121945920121946003E069-33654
chr8121972229121973105E070-6552
chr8121945002121945454E071-34203
chr8121945502121945872E071-33785
chr8121945920121946003E071-33654
chr8121946044121946162E071-33495
chr8121946193121946251E071-33406
chr8121945002121945454E072-34203
chr8121945502121945872E072-33785
chr8121945920121946003E072-33654
chr8121946044121946162E072-33495
chr8121946193121946251E072-33406
chr8121945002121945454E073-34203
chr8121945502121945872E073-33785
chr8121945920121946003E073-33654
chr8121945002121945454E074-34203
chr8121945502121945872E074-33785
chr8121945920121946003E074-33654
chr8121965369121965461E081-14196
chr8121965509121965563E081-14094
chr8121965682121965737E081-13920
chr8121965937121966187E081-13470
chr8121967350121967436E081-12221
chr8121967861121968080E081-11577
chr8122001050122001802E08121393
chr8122001814122002166E08122157
chr8121949997121950051E082-29606
chr8121950076121950624E082-29033
chr8121971849121972024E082-7633
chr8121972229121973105E082-6552