rs9397270

Homo sapiens
T>C
LOC101928923 : Intron Variant
LOC105378072 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T==0424 (12610/29690,GnomAD)
T==0405 (11795/29118,TOPMED)
T==0345 (1729/5008,1000G)
C=0478 (1843/3854,ALSPAC)
C=0475 (1760/3708,TWINSUK)
chr6:155842664 (GRCh38.p7) (6q25.3)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.155842664T>C
GRCh37.p13 chr 6NC_000006.11:g.156163798T>C

Gene: LOC101928923, uncharacterized LOC101928923(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC101928923 transcriptXR_001744423.1:n.N/AIntron Variant

Gene: LOC105378072, uncharacterized LOC105378072(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105378072 transcriptXR_001744424.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.323C=0.677
1000GenomesAmericanSub694T=0.310C=0.690
1000GenomesEast AsianSub1008T=0.214C=0.786
1000GenomesEuropeSub1006T=0.522C=0.478
1000GenomesGlobalStudy-wide5008T=0.345C=0.655
1000GenomesSouth AsianSub978T=0.350C=0.650
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.522C=0.478
The Genome Aggregation DatabaseAfricanSub8672T=0.352C=0.648
The Genome Aggregation DatabaseAmericanSub826T=0.330C=0.670
The Genome Aggregation DatabaseEast AsianSub1614T=0.172C=0.828
The Genome Aggregation DatabaseEuropeSub18278T=0.483C=0.516
The Genome Aggregation DatabaseGlobalStudy-wide29690T=0.424C=0.575
The Genome Aggregation DatabaseOtherSub300T=0.540C=0.460
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.405C=0.594
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.525C=0.475
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs93972700.000793alcohol dependence20201924

eQTL of rs9397270 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9397270 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr6156200911156201278E07137113