rs9423593

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0286 (8555/29910,GnomAD)
T=0264 (7689/29118,TOPMED)
T=0201 (1009/5008,1000G)
T=0361 (1390/3854,ALSPAC)
T=0362 (1342/3708,TWINSUK)
chr10:5290386 (GRCh38.p7) (10p15.1)
AD
GWASdb2
1   publication(s)
See rs on genome
95 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.5290386C>T
GRCh37.p13 chr 10 fix patch HG871_PATCHNW_003871071.1:g.320052C>T
GRCh37.p13 chr 10NC_000010.10:g.5332349C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.881T=0.119
1000GenomesAmericanSub694C=0.710T=0.290
1000GenomesEast AsianSub1008C=0.894T=0.106
1000GenomesEuropeSub1006C=0.635T=0.365
1000GenomesGlobalStudy-wide5008C=0.799T=0.201
1000GenomesSouth AsianSub978C=0.820T=0.180
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.639T=0.361
The Genome Aggregation DatabaseAfricanSub8708C=0.839T=0.161
The Genome Aggregation DatabaseAmericanSub834C=0.690T=0.310
The Genome Aggregation DatabaseEast AsianSub1618C=0.910T=0.090
The Genome Aggregation DatabaseEuropeSub18450C=0.639T=0.360
The Genome Aggregation DatabaseGlobalStudy-wide29910C=0.714T=0.286
The Genome Aggregation DatabaseOtherSub300C=0.710T=0.290
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.735T=0.264
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.638T=0.362
PMID Title Author Journal
23691058Dosage transmission disequilibrium test (dTDT) for linkage and association detection.Zhang ZPLoS One

P-Value

SNP ID p-value Traits Study
rs94235938.32E-06alcohol dependence23691058

eQTL of rs9423593 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9423593 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr10290440290490E067-29562
chr10290985291116E067-28936
chr10321004321089E067952
chr10338932338982E06718880
chr10339171339221E06719119
chr10339288339338E06719236
chr10339542339638E06719490
chr10340144340306E06720092
chr10343106343831E06723054
chr10343924344003E06723872
chr10344049344318E06723997
chr10338932338982E06818880
chr10339171339221E06819119
chr10339288339338E06819236
chr10339542339638E06819490
chr10340144340306E06820092
chr10343106343831E06823054
chr10343924344003E06823872
chr10344049344318E06823997
chr10344403344453E06824351
chr10344740344858E06824688
chr10287477287640E069-32412
chr10290440290490E069-29562
chr10321004321089E069952
chr10338932338982E06918880
chr10339171339221E06919119
chr10339288339338E06919236
chr10339542339638E06919490
chr10340144340306E06920092
chr10343106343831E06923054
chr10343924344003E06923872
chr10344049344318E06923997
chr10287923288291E070-31761
chr10288443288559E070-31493
chr10321004321089E070952
chr10287477287640E071-32412
chr10321004321089E071952
chr10335847336053E07115795
chr10336089336191E07116037
chr10336373336438E07116321
chr10336950336990E07116898
chr10338932338982E07118880
chr10339171339221E07119119
chr10339288339338E07119236
chr10339542339638E07119490
chr10340144340306E07120092
chr10343106343831E07123054
chr10343924344003E07123872
chr10344049344318E07123997
chr10344403344453E07124351
chr10287477287640E072-32412
chr10290440290490E072-29562
chr10321004321089E072952
chr10328668328794E0728616
chr10338932338982E07218880
chr10339171339221E07219119
chr10339288339338E07219236
chr10339542339638E07219490
chr10340144340306E07220092
chr10343106343831E07223054
chr10343924344003E07223872
chr10344049344318E07223997
chr10344403344453E07224351
chr10339542339638E07319490
chr10340144340306E07320092
chr10343106343831E07323054
chr10287477287640E074-32412
chr10287923288291E074-31761
chr10290440290490E074-29562
chr10317286317666E074-2386
chr10321004321089E074952
chr10335847336053E07415795
chr10336089336191E07416037
chr10336373336438E07416321
chr10338932338982E07418880
chr10339171339221E07419119
chr10339288339338E07419236
chr10339542339638E07419490
chr10340144340306E07420092
chr10343106343831E07423054
chr10343924344003E07423872
chr10344049344318E07423997
chr10344403344453E07424351
chr10344740344858E07424688
chr10287477287640E081-32412
chr10291259291444E081-28608
chr10291506291586E081-28466
chr10291655291723E081-28329
chr10291842292190E081-27862
chr10352079352249E08232027
chr10352252352502E08232200
chr10352608353131E08232556
chr10356266356354E08236214
chr10356392356451E08236340
chr10356518356595E08236466