rs9425128

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0476 (14201/29790,GnomAD)
T=0460 (13399/29118,TOPMED)
C==0497 (2487/5008,1000G)
T=0421 (1623/3854,ALSPAC)
T=0420 (1558/3708,TWINSUK)
chr1:73703600 (GRCh38.p7) (1p31.1)
AD
GWASdb2
1   publication(s)
See rs on genome
5 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.73703600C>T
GRCh37.p13 chr 1NC_000001.10:g.74169283C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.463T=0.537
1000GenomesAmericanSub694C=0.730T=0.270
1000GenomesEast AsianSub1008C=0.404T=0.596
1000GenomesEuropeSub1006C=0.572T=0.428
1000GenomesGlobalStudy-wide5008C=0.497T=0.503
1000GenomesSouth AsianSub978C=0.390T=0.610
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.579T=0.421
The Genome Aggregation DatabaseAfricanSub8678C=0.490T=0.510
The Genome Aggregation DatabaseAmericanSub824C=0.690T=0.310
The Genome Aggregation DatabaseEast AsianSub1576C=0.419T=0.581
The Genome Aggregation DatabaseEuropeSub18410C=0.539T=0.460
The Genome Aggregation DatabaseGlobalStudy-wide29790C=0.523T=0.476
The Genome Aggregation DatabaseOtherSub302C=0.560T=0.440
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.539T=0.460
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.580T=0.420
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs94251280.000627alcohol dependence20201924

eQTL of rs9425128 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9425128 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr17413974674139979E081-29304
chr17414035974140424E081-28859
chr17414074774140902E081-28381
chr17418270374183250E08113420
chr17418370174184025E08114418