rs9492684

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0213 (6383/29888,GnomAD)
C=0231 (6742/29118,TOPMED)
C=0305 (1527/5008,1000G)
C=0139 (534/3854,ALSPAC)
C=0141 (521/3708,TWINSUK)
chr6:130647858 (GRCh38.p7) (6q23.1)
ND
GWASdb2
1   publication(s)
See rs on genome
4 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.130647858A>C
GRCh37.p13 chr 6NC_000006.11:g.130969003A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.613C=0.387
1000GenomesAmericanSub694A=0.780C=0.220
1000GenomesEast AsianSub1008A=0.529C=0.471
1000GenomesEuropeSub1006A=0.856C=0.144
1000GenomesGlobalStudy-wide5008A=0.695C=0.305
1000GenomesSouth AsianSub978A=0.750C=0.250
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.861C=0.139
The Genome Aggregation DatabaseAfricanSub8688A=0.659C=0.341
The Genome Aggregation DatabaseAmericanSub830A=0.760C=0.240
The Genome Aggregation DatabaseEast AsianSub1610A=0.576C=0.424
The Genome Aggregation DatabaseEuropeSub18458A=0.864C=0.135
The Genome Aggregation DatabaseGlobalStudy-wide29888A=0.786C=0.213
The Genome Aggregation DatabaseOtherSub302A=0.840C=0.160
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.768C=0.231
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.859C=0.141
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs94926840.000851nicotine dependence17158188

eQTL of rs9492684 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9492684 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr6130954147130954327E068-14676
chr6130953250130953316E070-15687
chr6130953554130953685E070-15318
chr6130975111130975265E0706108