SNP Detail Info-rs9538710

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

TDRD3 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0123 (3690/29964,GnomAD)
A=0106 (3087/29116,TOPMED)
A=0129 (648/5008,1000G)
A=0163 (627/3854,ALSPAC)
A=0175 (650/3708,TWINSUK)

Position: chr13:60461664 (GRCh38.p7) (13q21.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 3 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 13	NC_000013.11:g.60461664G>A
GRCh37.p13 chr 13	NC_000013.10:g.61035798G>A

Molecule type	Change	Amino acid[Codon]	SO Term
TDRD3 transcript variant 1	NM_001146070.1:c.	N/A	Intron Variant
TDRD3 transcript variant 3	NM_001146071.1:c.	N/A	Intron Variant
TDRD3 transcript variant 2	NM_030794.2:c.	N/A	Intron Variant
TDRD3 transcript variant X2	XM_005266556.4:c.	N/A	Intron Variant
TDRD3 transcript variant X7	XM_005266560.2:c.	N/A	Intron Variant
TDRD3 transcript variant X1	XM_011535247.1:c.	N/A	Intron Variant
TDRD3 transcript variant X7	XM_011535249.2:c.	N/A	Intron Variant
TDRD3 transcript variant X5	XM_017020777.1:c.	N/A	Intron Variant
TDRD3 transcript variant X3	XR_941666.2:n.	N/A	Intron Variant
TDRD3 transcript variant X4	XR_941667.1:n.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.973	A=0.027
1000Genomes	American	Sub	694	G=0.830	A=0.170
1000Genomes	East Asian	Sub	1008	G=0.815	A=0.185
1000Genomes	Europe	Sub	1006	G=0.876	A=0.124
1000Genomes	Global	Study-wide	5008	G=0.871	A=0.129
1000Genomes	South Asian	Sub	978	G=0.820	A=0.180
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.837	A=0.163
The Genome Aggregation Database	African	Sub	8730	G=0.959	A=0.041
The Genome Aggregation Database	American	Sub	836	G=0.870	A=0.130
The Genome Aggregation Database	East Asian	Sub	1612	G=0.797	A=0.203
The Genome Aggregation Database	Europe	Sub	18484	G=0.845	A=0.154
The Genome Aggregation Database	Global	Study-wide	29964	G=0.876	A=0.123
The Genome Aggregation Database	Other	Sub	302	G=0.870	A=0.130
Trans-Omics for Precision Medicine	Global	Study-wide	29116	G=0.894	A=0.106
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.825	A=0.175

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs9538710	0.00077	alcohol dependence(early age of onset)	20201924
rs9538710	0.00085	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr13	60987505	60987654	E067	-48144
chr13	60985807	60985921	E068	-49877
chr13	61041280	61041556	E072	5482

rs9538710